of Gut microbiota has gained increasing interest in the pathogenesis immune-related diseases. In this context, graft-versus-host disease is a condition characterized by an immune response which frequently complicates and limits the outcomes of hematopoietic stem cell transplantations. Past studies, carried mostly in animals, already supported a relationship between gut microbiota and graft-versus-host disease. However, the possible mechanisms underlying this connection remain elusory. Moreover, strategies to prevent graft-versus-host disease are of great interest as well as the potential role of gut microbiota modulation. We reviewed the role of gut microbiota in the development of immune system and its involvement in the graft-versus-host disease, focusing on data available on humans.

Laterza, L., Rizzatti, G., Gaetani, E., Chiusolo, P., Gasbarrini, A., THE GUT MICROBIOTA AND IMMUNE SYSTEM RELATIONSHIP IN HUMAN GRAFT-VERSUS-HOST DISEASE, <<MEDITERRANEAN JOURNAL OF HEMATOLOGY AND INFECTIOUS DISEASES>>, 2016; 8 (8): e2016025-e2016025. [doi:10.4084/mjhid.2016.025] [http://hdl.handle.net/10807/92925]

THE GUT MICROBIOTA AND IMMUNE SYSTEM RELATIONSHIP IN HUMAN GRAFT-VERSUS-HOST DISEASE

Laterza, Lucrezia
Primo
;
Gaetani, Eleonora;Chiusolo, Patrizia
Penultimo
;
Gasbarrini, Antonio
Ultimo
2016

Abstract

of Gut microbiota has gained increasing interest in the pathogenesis immune-related diseases. In this context, graft-versus-host disease is a condition characterized by an immune response which frequently complicates and limits the outcomes of hematopoietic stem cell transplantations. Past studies, carried mostly in animals, already supported a relationship between gut microbiota and graft-versus-host disease. However, the possible mechanisms underlying this connection remain elusory. Moreover, strategies to prevent graft-versus-host disease are of great interest as well as the potential role of gut microbiota modulation. We reviewed the role of gut microbiota in the development of immune system and its involvement in the graft-versus-host disease, focusing on data available on humans.
Inglese
Laterza, L., Rizzatti, G., Gaetani, E., Chiusolo, P., Gasbarrini, A., THE GUT MICROBIOTA AND IMMUNE SYSTEM RELATIONSHIP IN HUMAN GRAFT-VERSUS-HOST DISEASE, <<MEDITERRANEAN JOURNAL OF HEMATOLOGY AND INFECTIOUS DISEASES>>, 2016; 8 (8): e2016025-e2016025. [doi:10.4084/mjhid.2016.025] [http://hdl.handle.net/10807/92925]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10807/92925
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