The aim of this study is to correlate 3D magnetic resonance spectroscopy results with prostate-specific antigen (PSA) levels and with time since externalbeam irradiation (EBRT) to verify successful treatment by assessing the achievement of metabolic atrophy (MA). According to our results, MA detection increases with decreasing PSA levels and with increasing time on adjuvant hormone therapy after EBRT, which supports long-term treatment with hormonal therapy in advanced prostate cancer.
Valentini, A. L., Gui, B., D'Agostino, G. R., Mattiucci, G. C., Clementi, V., Di Molfetta, I. V., Bonomo, P., Mantini, G., Locally Advanced Prostate Cancer: Three-DimensionalMagnetic Resonance Spectroscopy to Monitor ProstateResponse to Therapy, <<INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS>>, 2012; 2012 (84): 719-724. [doi:doi: 10.1016/j.ijrobp.2011.12.089] [http://hdl.handle.net/10807/92892]
Locally Advanced Prostate Cancer: Three-Dimensional Magnetic Resonance Spectroscopy to Monitor Prostate Response to Therapy
Valentini, Anna Lia;Gui, Benedetta;D'Agostino, Giuseppe Roberto;Mattiucci, Gian Carlo;Di Molfetta, Ippolita Valentina;Mantini, Giovanna
2011
Abstract
The aim of this study is to correlate 3D magnetic resonance spectroscopy results with prostate-specific antigen (PSA) levels and with time since externalbeam irradiation (EBRT) to verify successful treatment by assessing the achievement of metabolic atrophy (MA). According to our results, MA detection increases with decreasing PSA levels and with increasing time on adjuvant hormone therapy after EBRT, which supports long-term treatment with hormonal therapy in advanced prostate cancer.
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