The GHap R package was designed to call haplotypes from phased marker data. Given user-defined haplotype blocks (HapBlock), the package identifies the different haplotype alleles (HapAllele) present in the data and scores sample haplotype allele genotypes (HapGenotype) based on HapAllele dose (i.e. 0, 1 or 2 copies). The output is not only useful for analyses that can handle multi-allelic markers, but is also conveniently formatted for existing pipelines intended for bi-allelic markers.
Utsunomiya, Y. T., Milanesi, M., Utsunomiya, A. T. H., Ajmone Marsan, P., Garcia, J. F., GHap: an R package for genome-wide haplotyping, <<BIOINFORMATICS>>, 2016; 32 (18): 2861-2-2862. [doi:10.1093/bioinformatics/btw356] [http://hdl.handle.net/10807/91442]
Autori: | ||
Titolo: | GHap: an R package for genome-wide haplotyping | |
Digital Object Identifier (DOI): | http://dx.doi.org/10.1093/bioinformatics/btw356 | |
Data di pubblicazione: | 2016 | |
Abstract: | The GHap R package was designed to call haplotypes from phased marker data. Given user-defined haplotype blocks (HapBlock), the package identifies the different haplotype alleles (HapAllele) present in the data and scores sample haplotype allele genotypes (HapGenotype) based on HapAllele dose (i.e. 0, 1 or 2 copies). The output is not only useful for analyses that can handle multi-allelic markers, but is also conveniently formatted for existing pipelines intended for bi-allelic markers. | |
Lingua: | Inglese | |
Rivista: | ||
Citazione: | Utsunomiya, Y. T., Milanesi, M., Utsunomiya, A. T. H., Ajmone Marsan, P., Garcia, J. F., GHap: an R package for genome-wide haplotyping, <<BIOINFORMATICS>>, 2016; 32 (18): 2861-2-2862. [doi:10.1093/bioinformatics/btw356] [http://hdl.handle.net/10807/91442] | |
Appare nelle tipologie: | Articolo in rivista, Nota a sentenza |