Food protein-induced enterocolitis syndrome (FPIES) is an allergic disease, probably non-IgE-mediated, with expression predominantly in the GI tract. The most characteristic symptom is repeated, debilitating vomiting. It occurs 2-6 h after ingestion of culprit food and is usually accompanied by pallor and lethargy. There may be diarrhea, and in 10-20% of cases, severe hypotension. These symptoms resolve completely within a few hours. The food most frequently involved is cow's milk, followed by rice, but many other foods may be involved. The prognosis is generally good in a few years. In this review the authors try to cope, with the help of some case histories, with the practical clinical aspects of FPIES. The authors also try to provide a management approach based on current knowledge, and finally, to point out the aspects of FPIES that are still controversial.

Miceli Sopo, S., Greco, M., Monaco, S., Tripodi, S., Calvani, M., Food protein-induced enterocolitis syndrome, from practice to theory, <<EXPERT REVIEW OF CLINICAL IMMUNOLOGY>>, 2013; 9 (8): 707-715. [doi:10.1586/1744666X.2013.814418] [http://hdl.handle.net/10807/86038]

Food protein-induced enterocolitis syndrome, from practice to theory

Miceli Sopo, Stefano
Primo
;
Monaco, Serena;
2013

Abstract

Food protein-induced enterocolitis syndrome (FPIES) is an allergic disease, probably non-IgE-mediated, with expression predominantly in the GI tract. The most characteristic symptom is repeated, debilitating vomiting. It occurs 2-6 h after ingestion of culprit food and is usually accompanied by pallor and lethargy. There may be diarrhea, and in 10-20% of cases, severe hypotension. These symptoms resolve completely within a few hours. The food most frequently involved is cow's milk, followed by rice, but many other foods may be involved. The prognosis is generally good in a few years. In this review the authors try to cope, with the help of some case histories, with the practical clinical aspects of FPIES. The authors also try to provide a management approach based on current knowledge, and finally, to point out the aspects of FPIES that are still controversial.
Inglese
Miceli Sopo, S., Greco, M., Monaco, S., Tripodi, S., Calvani, M., Food protein-induced enterocolitis syndrome, from practice to theory, <<EXPERT REVIEW OF CLINICAL IMMUNOLOGY>>, 2013; 9 (8): 707-715. [doi:10.1586/1744666X.2013.814418] [http://hdl.handle.net/10807/86038]
File in questo prodotto:
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/10807/86038
Citazioni
  • ???jsp.display-item.citation.pmc??? 12
  • Scopus 47
  • ???jsp.display-item.citation.isi??? 44
social impact