HIV RNA monitoring is not available in most antiretroviral treatment (ART) programs in sub-Saharan Africa; switch to second-line therapy is mostly guided by clinical/immunological criteria. This may lead to unnecessary disease progression and drug resistance accumulation. We investigated the prognostic value of virological and immunological status 6 months after ART initiation with respect to death, loss to follow-up, and treatment switch.

De Luca, A., Marazzi, M., Mancinelli, S., Ceffa, S., Altan, A., Buonomo, E., Prosperi, M., Pedruzzi, B., Noorjehan, A., Scarcella, P., Liotta, G., Palombi, L., Prognostic value of virological and immunological responses after 6 months of antiretroviral treatment in adults with HIV-1 infection in sub-Saharan Africa, <<JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES>>, 2012; 59 (3): 236-244. [doi:10.1097/QAI.0b013e31824276e9] [http://hdl.handle.net/10807/8325]

Prognostic value of virological and immunological responses after 6 months of antiretroviral treatment in adults with HIV-1 infection in sub-Saharan Africa

De Luca, Andrea;Pedruzzi, Barbara;
2012

Abstract

HIV RNA monitoring is not available in most antiretroviral treatment (ART) programs in sub-Saharan Africa; switch to second-line therapy is mostly guided by clinical/immunological criteria. This may lead to unnecessary disease progression and drug resistance accumulation. We investigated the prognostic value of virological and immunological status 6 months after ART initiation with respect to death, loss to follow-up, and treatment switch.
2012
Inglese
De Luca, A., Marazzi, M., Mancinelli, S., Ceffa, S., Altan, A., Buonomo, E., Prosperi, M., Pedruzzi, B., Noorjehan, A., Scarcella, P., Liotta, G., Palombi, L., Prognostic value of virological and immunological responses after 6 months of antiretroviral treatment in adults with HIV-1 infection in sub-Saharan Africa, <<JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES>>, 2012; 59 (3): 236-244. [doi:10.1097/QAI.0b013e31824276e9] [http://hdl.handle.net/10807/8325]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10807/8325
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