Cytokines are immunal regulatory proteins, however they also play a relevant role in inflammatory diseases. IL-31 is a newly discovered cytokine expressed primarily in TH2 cells, introduced by activated CD4+ T cells. IL-31 is capable of inducing chemokines and other cytokines in several inflammatory diseases via its surface receptor. This cytokine is also produced by mast cells and mast cell line, suggesting a role in allergic diseases. In this editorial we revisit the biological role of IL-31 in immunity and inflammation.

Castellani, M., Felaco, P., Galzio, R. J., Tripodi, D., Toniato, E., De Lutiis, M. A., Fulcheri, M., Caraffa, A., Antinolfi, P., Tete, S., Felaco, M., Conti, F., Pandolfi, F., Theoharides, T. C., Shaiki Dathagirisaheb, Y. B., IL-31 a Th2 cytokine involved in immunity and inflammation., <<INTERNATIONAL JOURNAL OF IMMUNOPATHOLOGY AND PHARMACOLOGY>>, 2010; (Luglio): 709-713 [http://hdl.handle.net/10807/8050]

IL-31 a Th2 cytokine involved in immunity and inflammation.

Pandolfi, Franco;
2010

Abstract

Cytokines are immunal regulatory proteins, however they also play a relevant role in inflammatory diseases. IL-31 is a newly discovered cytokine expressed primarily in TH2 cells, introduced by activated CD4+ T cells. IL-31 is capable of inducing chemokines and other cytokines in several inflammatory diseases via its surface receptor. This cytokine is also produced by mast cells and mast cell line, suggesting a role in allergic diseases. In this editorial we revisit the biological role of IL-31 in immunity and inflammation.
2010
Inglese
Castellani, M., Felaco, P., Galzio, R. J., Tripodi, D., Toniato, E., De Lutiis, M. A., Fulcheri, M., Caraffa, A., Antinolfi, P., Tete, S., Felaco, M., Conti, F., Pandolfi, F., Theoharides, T. C., Shaiki Dathagirisaheb, Y. B., IL-31 a Th2 cytokine involved in immunity and inflammation., <<INTERNATIONAL JOURNAL OF IMMUNOPATHOLOGY AND PHARMACOLOGY>>, 2010; (Luglio): 709-713 [http://hdl.handle.net/10807/8050]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10807/8050
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