IL-18 is produced by many cell types, such as Kupffer cells, keratinocytes, macrophages, dendritic cells, and activated T cells stimulated by LPS. It is an important regulator of both innate and acquired immune responses. IL-18 plays a central role in rheumatoid arthritis since the T cells and macrophages that invade the synovial. These finding support a role for IL-18 in inflammation, allergy and immune diseases.

Tripodi, D., Macauro, G., Anogeianaki, A., Castellani, M. L., Pandolfi, F., Felaco, P., Toniato, E., De Lutiis, M. A., Fulcheri, M., Tete, S., Galzio, R., Salini, V., Caraffa, A., Antinolfi, P., Frydas, I., Sabatino, G., Shaik Dasthagirisaheb, Y. B., Impact of IL-18 on inflammation, <<JOURNAL OF BIOLOGICAL REGULATORS & HOMEOSTATIC AGENTS>>, 2012; (Gennaio): 7-11 [http://hdl.handle.net/10807/7981]

Impact of IL-18 on inflammation

Tripodi, Domenico;Pandolfi, Franco;
2011

Abstract

IL-18 is produced by many cell types, such as Kupffer cells, keratinocytes, macrophages, dendritic cells, and activated T cells stimulated by LPS. It is an important regulator of both innate and acquired immune responses. IL-18 plays a central role in rheumatoid arthritis since the T cells and macrophages that invade the synovial. These finding support a role for IL-18 in inflammation, allergy and immune diseases.
Inglese
Tripodi, D., Macauro, G., Anogeianaki, A., Castellani, M. L., Pandolfi, F., Felaco, P., Toniato, E., De Lutiis, M. A., Fulcheri, M., Tete, S., Galzio, R., Salini, V., Caraffa, A., Antinolfi, P., Frydas, I., Sabatino, G., Shaik Dasthagirisaheb, Y. B., Impact of IL-18 on inflammation, <<JOURNAL OF BIOLOGICAL REGULATORS & HOMEOSTATIC AGENTS>>, 2012; (Gennaio): 7-11 [http://hdl.handle.net/10807/7981]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10807/7981
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