IRIS PubliCatt
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EnglishWe describe a patient suffering from seropositive rheumatoid arthritis (RA) and type I diabetes mellitus (T1DM), who achieved a good EULAR response together with an improvement of the glycemic profile under treatment with CTLA-4 Ig. A close association is known to exist between T1DM and RA, and CTLA-4 exon 1 polymorphism has been associated to RA with coexisting autoimmune endocrinopathies. The possible common genetic background and the potential role of CTLA-4 Ig in the early phases of T1DM, could be considered in the therapeutic interventions in RA patients with type 1 diabetes.
Fedele, A. L., Alivernini, S., Gremese, E., Ferraccioli, G., CTLA-4 Ig as an effective treatment in a patient with type I diabetes mellitus and seropositive rheumatoid arthritis, <<CLINICAL AND EXPERIMENTAL RHEUMATOLOGY>>, 2016; 34 (2): 315-317 [http://hdl.handle.net/10807/78573]
| Autori: | ||
| Titolo: | CTLA-4 Ig as an effective treatment in a patient with type I diabetes mellitus and seropositive rheumatoid arthritis | |
| Data di pubblicazione: | 2016 | |
| Abstract: | We describe a patient suffering from seropositive rheumatoid arthritis (RA) and type I diabetes mellitus (T1DM), who achieved a good EULAR response together with an improvement of the glycemic profile under treatment with CTLA-4 Ig. A close association is known to exist between T1DM and RA, and CTLA-4 exon 1 polymorphism has been associated to RA with coexisting autoimmune endocrinopathies. The possible common genetic background and the potential role of CTLA-4 Ig in the early phases of T1DM, could be considered in the therapeutic interventions in RA patients with type 1 diabetes. | |
| Lingua: | Inglese | |
| Rivista: | ||
| Citazione: | Fedele, A. L., Alivernini, S., Gremese, E., Ferraccioli, G., CTLA-4 Ig as an effective treatment in a patient with type I diabetes mellitus and seropositive rheumatoid arthritis, <<CLINICAL AND EXPERIMENTAL RHEUMATOLOGY>>, 2016; 34 (2): 315-317 [http://hdl.handle.net/10807/78573] | |
| Appare nelle tipologie: | Articolo in rivista, Nota a sentenza |
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