We describe a patient with progressive disorder of speech, without language impairment (opercular syndrome). Morphometric analysis confirmed asymmetric volume reduction of the precentral areas (>left). Diffusion imaging showed significant white matter changes in the left frontal lobe, with specific involvement of the left corticobulbar tract and connections between supplementary/pre-supplementary motor areas and the frontal operculum (frontal aslant tract). We suggest that the organization of expressive language includes a 'low level' motor system principally distributed in the left hemisphere that shows specific susceptibility to neurodegeneration, distinct from neural systems subtending praxic, and cognitive aspects of language.

Silveri, M. C., Incordino, F., Lo Monaco, R., Bizzarro, A., Masullo, C., Piludu, F., Colosimo, C., Neural substrates of the 'low-level' system for speech articulation: Evidence from primary opercular syndrome, <<JOURNAL OF NEUROPSYCHOLOGY>>, 2016; 2016 (11): 450-457. [doi:10.1111/jnp.12099] [http://hdl.handle.net/10807/76709]

Neural substrates of the 'low-level' system for speech articulation: Evidence from primary opercular syndrome

Silveri, Maria Caterina;Bizzarro, Alessandra;Masullo, Carlo;Piludu, Francesca;Colosimo, Cesare
2016

Abstract

We describe a patient with progressive disorder of speech, without language impairment (opercular syndrome). Morphometric analysis confirmed asymmetric volume reduction of the precentral areas (>left). Diffusion imaging showed significant white matter changes in the left frontal lobe, with specific involvement of the left corticobulbar tract and connections between supplementary/pre-supplementary motor areas and the frontal operculum (frontal aslant tract). We suggest that the organization of expressive language includes a 'low level' motor system principally distributed in the left hemisphere that shows specific susceptibility to neurodegeneration, distinct from neural systems subtending praxic, and cognitive aspects of language.
eng
Silveri, M. C., Incordino, F., Lo Monaco, R., Bizzarro, A., Masullo, C., Piludu, F., Colosimo, C., Neural substrates of the 'low-level' system for speech articulation: Evidence from primary opercular syndrome, <>, 2016; 2016 (11): 450-457. [doi:10.1111/jnp.12099] [http://hdl.handle.net/10807/76709]
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/10807/76709
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