BACKGROUND: During recent years, a new population of HIV and HCV co-infected subjects has emerged presenting particular oral problems. The aim of our study was to determine the prevalence of oral lesions in HIV+ subjects and HIV and HCV co-infected subjects, to assess whether co-infection is a risk factor for the presence of oral lesions. METHODS: 200 HIV+ subjects were consecutively enrolled, divided into two groups: Group 1 (130 HIV+ subjects) and Group 2 (70 HIV-HCV co-infected subjects) and visited by two oral medicine specialists. Epidemiological, laboratory and clinical parameters were gathered to determine the possible risk factors for oral lesions. RESULTS: 52 on 200 subjects (26%) presented oral lesions: in Group 1, 25 on 130 subjects (19.23%) presented oral lesions, whereas in Group 2, 27 on 70 subjects (38.57%) presented oral lesions. Multivariate analysis showed that the following variables are statistically associated with the presence of oral lesions: HIV-HCV co-infection (OR = 2.32; 95% CI = 1.01-5.33: P < 0.05) and the use of drugs for the treatment of systemic diseases not associated with HIV (OR = 4.34; 95% CI = 1.78-5.33: P = 0.005). CONCLUSIONS: It is possible to assess, on the basis of our results, that co-infected patients are more prone than HIV mono-infected patients to develop oral lesions and thus should undergo strict oral medicine monitoring.

Giuliani, M., Lajolo, C., Sartorio, A., Ammassari, A., Lacaita, M. G., Scivetti, M., Tamburrini, E., Tumbarello, M., Oral lesions in HIV and HCV co-infected individuals in HAART era, <<JOURNAL OF ORAL PATHOLOGY & MEDICINE>>, 2008; 2008 (37): 468-474 [http://hdl.handle.net/10807/7619]

Oral lesions in HIV and HCV co-infected individuals in HAART era

Giuliani, Michele;Lajolo, Carlo;Sartorio, Alessandra;Ammassari, Adriana;Tamburrini, Enrica;Tumbarello, Mario
2008

Abstract

BACKGROUND: During recent years, a new population of HIV and HCV co-infected subjects has emerged presenting particular oral problems. The aim of our study was to determine the prevalence of oral lesions in HIV+ subjects and HIV and HCV co-infected subjects, to assess whether co-infection is a risk factor for the presence of oral lesions. METHODS: 200 HIV+ subjects were consecutively enrolled, divided into two groups: Group 1 (130 HIV+ subjects) and Group 2 (70 HIV-HCV co-infected subjects) and visited by two oral medicine specialists. Epidemiological, laboratory and clinical parameters were gathered to determine the possible risk factors for oral lesions. RESULTS: 52 on 200 subjects (26%) presented oral lesions: in Group 1, 25 on 130 subjects (19.23%) presented oral lesions, whereas in Group 2, 27 on 70 subjects (38.57%) presented oral lesions. Multivariate analysis showed that the following variables are statistically associated with the presence of oral lesions: HIV-HCV co-infection (OR = 2.32; 95% CI = 1.01-5.33: P < 0.05) and the use of drugs for the treatment of systemic diseases not associated with HIV (OR = 4.34; 95% CI = 1.78-5.33: P = 0.005). CONCLUSIONS: It is possible to assess, on the basis of our results, that co-infected patients are more prone than HIV mono-infected patients to develop oral lesions and thus should undergo strict oral medicine monitoring.
Inglese
Giuliani, M., Lajolo, C., Sartorio, A., Ammassari, A., Lacaita, M. G., Scivetti, M., Tamburrini, E., Tumbarello, M., Oral lesions in HIV and HCV co-infected individuals in HAART era, <<JOURNAL OF ORAL PATHOLOGY & MEDICINE>>, 2008; 2008 (37): 468-474 [http://hdl.handle.net/10807/7619]
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/10807/7619
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