Meta-analyses show that nonbound ceruloplasmin (non-Cp) copper (also known as free or labile copper) in serum is higher in patients with Alzheimer disease (AD). It differentiates subjects with mild cognitive impairment (MCI) from healthy controls. However, a longitudinal study on an MCI cohort has not yet been performed to assess the accuracy of non-Cp copper for the prediction of conversion from MCI to AD during a long-term follow-up.

Squitti, R., Ghidoni, R., Siotto, M., Ventriglia, M., Benussi, L., Paterlini, A., Magri, M., Binetti, G., Cassetta, E., Caprara, D., Vernieri, F., Rossini, P. M., Pasqualetti, P., Value of serum nonceruloplasmin copper for prediction of mild cognitive impairment conversion to Alzheimer disease, <<ANNALS OF NEUROLOGY>>, 2014; 75 (4): 574-580. [doi:10.1002/ana.24136] [http://hdl.handle.net/10807/72452]

Value of serum nonceruloplasmin copper for prediction of mild cognitive impairment conversion to Alzheimer disease

Rossini, Paolo Maria;
2014

Abstract

Meta-analyses show that nonbound ceruloplasmin (non-Cp) copper (also known as free or labile copper) in serum is higher in patients with Alzheimer disease (AD). It differentiates subjects with mild cognitive impairment (MCI) from healthy controls. However, a longitudinal study on an MCI cohort has not yet been performed to assess the accuracy of non-Cp copper for the prediction of conversion from MCI to AD during a long-term follow-up.
Inglese
Squitti, R., Ghidoni, R., Siotto, M., Ventriglia, M., Benussi, L., Paterlini, A., Magri, M., Binetti, G., Cassetta, E., Caprara, D., Vernieri, F., Rossini, P. M., Pasqualetti, P., Value of serum nonceruloplasmin copper for prediction of mild cognitive impairment conversion to Alzheimer disease, <<ANNALS OF NEUROLOGY>>, 2014; 75 (4): 574-580. [doi:10.1002/ana.24136] [http://hdl.handle.net/10807/72452]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10807/72452
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