Meta-analyses show that nonbound ceruloplasmin (non-Cp) copper (also known as free or labile copper) in serum is higher in patients with Alzheimer disease (AD). It differentiates subjects with mild cognitive impairment (MCI) from healthy controls. However, a longitudinal study on an MCI cohort has not yet been performed to assess the accuracy of non-Cp copper for the prediction of conversion from MCI to AD during a long-term follow-up.
Squitti, R., Ghidoni, R., Siotto, M., Ventriglia, M., Benussi, L., Paterlini, A., Magri, M., Binetti, G., Cassetta, E., Caprara, D., Vernieri, F., Rossini, P. M., Pasqualetti, P., Value of serum nonceruloplasmin copper for prediction of mild cognitive impairment conversion to Alzheimer disease, <<ANNALS OF NEUROLOGY>>, 2014; 75 (4): 574-580. [doi:10.1002/ana.24136] [http://hdl.handle.net/10807/72452]
Autori: | ||
Titolo: | Value of serum nonceruloplasmin copper for prediction of mild cognitive impairment conversion to Alzheimer disease | |
Digital Object Identifier (DOI): | http://dx.doi.org/10.1002/ana.24136 | |
Data di pubblicazione: | 2014 | |
Abstract: | Meta-analyses show that nonbound ceruloplasmin (non-Cp) copper (also known as free or labile copper) in serum is higher in patients with Alzheimer disease (AD). It differentiates subjects with mild cognitive impairment (MCI) from healthy controls. However, a longitudinal study on an MCI cohort has not yet been performed to assess the accuracy of non-Cp copper for the prediction of conversion from MCI to AD during a long-term follow-up. | |
Lingua: | Inglese | |
Rivista: | ||
Citazione: | Squitti, R., Ghidoni, R., Siotto, M., Ventriglia, M., Benussi, L., Paterlini, A., Magri, M., Binetti, G., Cassetta, E., Caprara, D., Vernieri, F., Rossini, P. M., Pasqualetti, P., Value of serum nonceruloplasmin copper for prediction of mild cognitive impairment conversion to Alzheimer disease, <<ANNALS OF NEUROLOGY>>, 2014; 75 (4): 574-580. [doi:10.1002/ana.24136] [http://hdl.handle.net/10807/72452] | |
Appare nelle tipologie: | Articolo in rivista, Nota a sentenza |