Gluten proteins, the culprits in celiac disease (CD), show striking similarities in primary structure with human salivary proline-rich proteins (PRPs). Both are enriched in proline and glutamine residues that often occur consecutively in their sequences. We investigated potential differences in the spectrum of salivary PRPs in health and CD.

Tian, N., Messana, I., Leffler, D., Kelly, C., Hansen, J., Cabras, T., D'Alessandro, A., Schuppan, D., Castagnola, M., Helmerhorst, E., Salivary proline-rich proteins and gluten: Do structural similarities suggest a role in celiac disease?, <<PROTEOMICS. CLINICAL APPLICATIONS>>, 2015; 9 (9-10): 953-964. [doi:10.1002/prca.201400170] [http://hdl.handle.net/10807/72371]

Salivary proline-rich proteins and gluten: Do structural similarities suggest a role in celiac disease?

Castagnola, Massimo;
2015

Abstract

Gluten proteins, the culprits in celiac disease (CD), show striking similarities in primary structure with human salivary proline-rich proteins (PRPs). Both are enriched in proline and glutamine residues that often occur consecutively in their sequences. We investigated potential differences in the spectrum of salivary PRPs in health and CD.
2015
Inglese
Tian, N., Messana, I., Leffler, D., Kelly, C., Hansen, J., Cabras, T., D'Alessandro, A., Schuppan, D., Castagnola, M., Helmerhorst, E., Salivary proline-rich proteins and gluten: Do structural similarities suggest a role in celiac disease?, <<PROTEOMICS. CLINICAL APPLICATIONS>>, 2015; 9 (9-10): 953-964. [doi:10.1002/prca.201400170] [http://hdl.handle.net/10807/72371]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10807/72371
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