Human chitotriosidase (Chit) increases during the osteoclast differentiation and their activity. We demonstrated that serum Chit was significantly higher in osteoporotic subjects than in healthy control ones and revealed a negative correlation between Chit and bone mineral density (BMD). This is the first study showing a correlation between Chit and severe postmenopausal osteoporosis.
Musumeci, M., Palermo, A., D'onofrio, L., Vadalà, G., Greto, V., Di Stasio, E., Maddaloni, E., Di Rosa, M., Tibullo, D., Silvia, A., Napoli, N., Denaro, V., Manfrini, S., Serum chitotriosidase in postmenopausal women with severe osteoporosis, <<OSTEOPOROSIS INTERNATIONAL>>, 2016; 27 (2): 711-716. [doi:10.1007/s00198-015-3254-3] [http://hdl.handle.net/10807/72354]
Autori: | ||
Titolo: | Serum chitotriosidase in postmenopausal women with severe osteoporosis | |
Digital Object Identifier (DOI): | http://dx.doi.org/10.1007/s00198-015-3254-3 | |
Data di pubblicazione: | 2016 | |
Abstract: | Human chitotriosidase (Chit) increases during the osteoclast differentiation and their activity. We demonstrated that serum Chit was significantly higher in osteoporotic subjects than in healthy control ones and revealed a negative correlation between Chit and bone mineral density (BMD). This is the first study showing a correlation between Chit and severe postmenopausal osteoporosis. | |
Lingua: | Inglese | |
Rivista: | ||
Citazione: | Musumeci, M., Palermo, A., D'onofrio, L., Vadalà, G., Greto, V., Di Stasio, E., Maddaloni, E., Di Rosa, M., Tibullo, D., Silvia, A., Napoli, N., Denaro, V., Manfrini, S., Serum chitotriosidase in postmenopausal women with severe osteoporosis, <<OSTEOPOROSIS INTERNATIONAL>>, 2016; 27 (2): 711-716. [doi:10.1007/s00198-015-3254-3] [http://hdl.handle.net/10807/72354] | |
Appare nelle tipologie: | Articolo in rivista, Nota a sentenza |