Based on the findings of our review, the latest European Resuscitation Council and European Society of Intensive Care Medicine (ERC-ESICM) guidelines recommend that myoclonus should be used only in combination with other criteria to predict poor neurological outcome after cardiac arrest. A special reason for caution when using myoclonus as a predictor of poor outcome is the heterogeneity of its clinical manifestations, which may range from isolated, focal myoclonic jerks to a generalized, continuous and prolonged myoclonus, commonly described as ‘myoclonus status epilepticus’ or ‘status myoclonus". Results of earlier studies suggested that in patients resuscitated from cardiac arrest the prognosis of status myoclonus is consistently poor, while late-onset action myoclonus, also known as Lance-Adams syndrome, is often compatible with neurological recovery. Unfortunately, the study from Seder et al could not assess the prognosis of these different forms of myoclonus separately, since timing, persistence, and location of myoclonus were not recorded.

Sandroni, C., Nolan, J., Neurologically Favorable Outcome Is Still Possible Despite Myoclonus in Comatose Survivors of Cardiac Arrest, <<CRITICAL CARE MEDICINE>>, 2015; 43 (9): e396-e396-7. [doi:10.1097/CCM.0000000000001070] [http://hdl.handle.net/10807/72052]

Neurologically Favorable Outcome Is Still Possible Despite Myoclonus in Comatose Survivors of Cardiac Arrest

Sandroni, Claudio;
2015

Abstract

Based on the findings of our review, the latest European Resuscitation Council and European Society of Intensive Care Medicine (ERC-ESICM) guidelines recommend that myoclonus should be used only in combination with other criteria to predict poor neurological outcome after cardiac arrest. A special reason for caution when using myoclonus as a predictor of poor outcome is the heterogeneity of its clinical manifestations, which may range from isolated, focal myoclonic jerks to a generalized, continuous and prolonged myoclonus, commonly described as ‘myoclonus status epilepticus’ or ‘status myoclonus". Results of earlier studies suggested that in patients resuscitated from cardiac arrest the prognosis of status myoclonus is consistently poor, while late-onset action myoclonus, also known as Lance-Adams syndrome, is often compatible with neurological recovery. Unfortunately, the study from Seder et al could not assess the prognosis of these different forms of myoclonus separately, since timing, persistence, and location of myoclonus were not recorded.
2015
Inglese
Sandroni, C., Nolan, J., Neurologically Favorable Outcome Is Still Possible Despite Myoclonus in Comatose Survivors of Cardiac Arrest, <<CRITICAL CARE MEDICINE>>, 2015; 43 (9): e396-e396-7. [doi:10.1097/CCM.0000000000001070] [http://hdl.handle.net/10807/72052]
File in questo prodotto:
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10807/72052
Citazioni
  • ???jsp.display-item.citation.pmc??? 2
  • Scopus 10
  • ???jsp.display-item.citation.isi??? 9
social impact