the characterization of a novel yeast mitochondrial Mg2+ exporter adds one small tile to the mosaic of the complex cellular Mg2+ homeostasis, and confirms once again just how incredibly important and versatile it is. These findings show how basic research paves the way to translational implications. Mg2+ deficiency is implicated in an ever-increasing number of pathologies. If the existence of an analogous rescue mechanism could be confirmed in humans, such a finding might be exploited in the design of innovative, therapeutic strategies.
Trapani, V., Wolf Minotti, F., Mitochondrial magnesium to the rescue, <<MAGNESIUM RESEARCH>>, 2015; 28 (2): 79-84. [doi:10.1684/mrh.2015.0386] [http://hdl.handle.net/10807/71711]
Mitochondrial magnesium to the rescue
Trapani, Valentina;Wolf Minotti, Federica
2015
Abstract
the characterization of a novel yeast mitochondrial Mg2+ exporter adds one small tile to the mosaic of the complex cellular Mg2+ homeostasis, and confirms once again just how incredibly important and versatile it is. These findings show how basic research paves the way to translational implications. Mg2+ deficiency is implicated in an ever-increasing number of pathologies. If the existence of an analogous rescue mechanism could be confirmed in humans, such a finding might be exploited in the design of innovative, therapeutic strategies.
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