the characterization of a novel yeast mitochondrial Mg2+ exporter adds one small tile to the mosaic of the complex cellular Mg2+ homeostasis, and confirms once again just how incredibly important and versatile it is. These findings show how basic research paves the way to translational implications. Mg2+ deficiency is implicated in an ever-increasing number of pathologies. If the existence of an analogous rescue mechanism could be confirmed in humans, such a finding might be exploited in the design of innovative, therapeutic strategies.
Trapani, V., Wolf, F., Mitochondrial magnesium to the rescue, <<MAGNESIUM RESEARCH>>, 2015; 28 (2): 79-84. [doi:10.1684/mrh.2015.0386] [http://hdl.handle.net/10807/71711]
Autori: | |
Titolo: | Mitochondrial magnesium to the rescue |
Digital Object Identifier (DOI): | http://dx.doi.org/10.1684/mrh.2015.0386 |
Data di pubblicazione: | 2015 |
Abstract: | the characterization of a novel yeast mitochondrial Mg2+ exporter adds one small tile to the mosaic of the complex cellular Mg2+ homeostasis, and confirms once again just how incredibly important and versatile it is. These findings show how basic research paves the way to translational implications. Mg2+ deficiency is implicated in an ever-increasing number of pathologies. If the existence of an analogous rescue mechanism could be confirmed in humans, such a finding might be exploited in the design of innovative, therapeutic strategies. |
Lingua: | Inglese |
Rivista: | |
Citazione: | Trapani, V., Wolf, F., Mitochondrial magnesium to the rescue, <<MAGNESIUM RESEARCH>>, 2015; 28 (2): 79-84. [doi:10.1684/mrh.2015.0386] [http://hdl.handle.net/10807/71711] |
Appare nelle tipologie: | Articolo in rivista, Nota a sentenza |