the relationship between magnesium homeostasis and IBD is a very interesting issue, and has so far received less attention than it deserves. IBD represents an intriguing prototype of disorders associated with alterations of magnesium homeostasis, as it may interconnect several aspects: dietary intake, absorption, immuno-modulatory properties, dietary and inflammatory regulation of ion channels, tumor initiation/progression and healing processes. Clarifying the role of magnesium and magnesium channels in maintaining a healthy immune system and intestinal mucosa might contribute to the understanding of the pathogenesis of IBD and inflammation-associated cancer
Trapani, V., Wolf Minotti, F., Scaldaferri, F., Dietary magnesium: the magic mineral that protects from colon cancer?, <<MAGNESIUM RESEARCH>>, 2015; 28 (3): 108-111. [doi:10.1684/mrh.2015.0390] [http://hdl.handle.net/10807/71709]
Dietary magnesium: the magic mineral that protects from colon cancer?
Trapani, Valentina;Wolf Minotti, Federica;Scaldaferri, Franco
2015
Abstract
the relationship between magnesium homeostasis and IBD is a very interesting issue, and has so far received less attention than it deserves. IBD represents an intriguing prototype of disorders associated with alterations of magnesium homeostasis, as it may interconnect several aspects: dietary intake, absorption, immuno-modulatory properties, dietary and inflammatory regulation of ion channels, tumor initiation/progression and healing processes. Clarifying the role of magnesium and magnesium channels in maintaining a healthy immune system and intestinal mucosa might contribute to the understanding of the pathogenesis of IBD and inflammation-associated cancer
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