The Minimal Model, (MM), used to assess insulin sensitivity (IS) from Intra-Venous Glucose-Tolerance Test (IVGTT) data, suffers from frequent lack of identifiability (parameter estimates with Coefficients of Variation (CV) less than 52%). The recently proposed Single Delay Model (SDM) is evaluated as a practical alternative.
Panunzi, S., De Gaetano, A., Mingrone, G., Advantages of the single delay model for the assessment of insulin sensitivity from the intravenous glucose tolerance test, <<THEORETICAL BIOLOGY AND MEDICAL MODELLING>>, 2010; 7 (Marzo): 9-9. [doi:10.1186/1742-4682-7-9] [http://hdl.handle.net/10807/7140]
Advantages of the single delay model for the assessment of insulin sensitivity from the intravenous glucose tolerance test
Panunzi, Simona;De Gaetano, Andrea;Mingrone, Geltrude
2010
Abstract
The Minimal Model, (MM), used to assess insulin sensitivity (IS) from Intra-Venous Glucose-Tolerance Test (IVGTT) data, suffers from frequent lack of identifiability (parameter estimates with Coefficients of Variation (CV) less than 52%). The recently proposed Single Delay Model (SDM) is evaluated as a practical alternative.
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