In the present article we report cytomegalovirus (CMV) DNA localization in the inner ear of a 15-month-old deaf boy 1 month after a virologically documented primary infection. CMV DNA retrieval was possible thanks to polymerase chain reaction analysis of the perilymph collected at cochlear implant surgery. To the authors' knowledge this is the first demonstration of CMV persistence in the cochlea of an immunocompetent subject after an acquired infection.
Di Nardo, W., Cattani, P., Scorpecci, A., Giannantonio, S., D'Onghia, S., Fadda, G., Paludetti, G., Cytomegalovirus DNA retrieval in the inner ear fluids of a congenitally deaf child one month after primary infection: a case report, <<THE LARYNGOSCOPE>>, 2011; 121 (4): 828-830. [doi:10.1002/lary.21447] [http://hdl.handle.net/10807/7110]
Cytomegalovirus DNA retrieval in the inner ear fluids of a congenitally deaf child one month after primary infection: a case report
Di Nardo, Walter;Cattani, Paola;Scorpecci, Alessandro;Giannantonio, Sara;D'Onghia, Sara;Fadda, Guido;Paludetti, Gaetano
2011
Abstract
In the present article we report cytomegalovirus (CMV) DNA localization in the inner ear of a 15-month-old deaf boy 1 month after a virologically documented primary infection. CMV DNA retrieval was possible thanks to polymerase chain reaction analysis of the perilymph collected at cochlear implant surgery. To the authors' knowledge this is the first demonstration of CMV persistence in the cochlea of an immunocompetent subject after an acquired infection.
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