Subtype A accounts for only 12% of HIV-1 infections worldwide but predominates in Russia and Former Soviet Union countries of Eastern Europe. After an early propagation via heterosexual contacts, this variant spread explosively among intravenous drug users. A distinct A1 variant predominates in Greece and Albania, which penetrated directly from Africa. Clade A1 accounts for 12.5% of non-B subtypes in Italy, being the most frequent after F1 subtype.
Lai, A., Bozzi, G., Franzetti, M., Binda, F., Simonetti, F., De Luca, A., Micheli, V., Meraviglia, P., Bagnarelli, P., Di Biagio, A., Monno, L., Saladini, F., Zazzi, M., Zehender, G., Ciccozzi, M., Balotta, C., HIV-1 A1 Subtype Epidemic in Italy Originated from Africa and Eastern Europe and Shows a High Frequency of Transmission Chains Involving Intravenous Drug Users, <<PLOS ONE>>, 2016; 11 (1): e0146097-e0146097. [doi:10.1371/journal.pone.0146097] [http://hdl.handle.net/10807/70748]
HIV-1 A1 Subtype Epidemic in Italy Originated from Africa and Eastern Europe and Shows a High Frequency of Transmission Chains Involving Intravenous Drug Users
De Luca, Andrea;
2016
Abstract
Subtype A accounts for only 12% of HIV-1 infections worldwide but predominates in Russia and Former Soviet Union countries of Eastern Europe. After an early propagation via heterosexual contacts, this variant spread explosively among intravenous drug users. A distinct A1 variant predominates in Greece and Albania, which penetrated directly from Africa. Clade A1 accounts for 12.5% of non-B subtypes in Italy, being the most frequent after F1 subtype.
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