In this study we tested the hypothesis that tapentadol inhibits GGRP release from the rat brainstem through a mechanism mediated by the inhibition of NA reuptake; as a second alternative hypothesis, we investigated whether tapentadol inhibits GGRP release via the inhibition of 5-HT reuptake.
Greco, M. C., Navarra, P., Tringali, G., The analgesic agent tapentadol inhibits calcitonin gene-related peptide release from isolated rat brainstem via a serotonergic mechanism, <<LIFE SCIENCES>>, 2016; (N/A): N/A-N/A. [doi:10.1016/j.lfs.2015.12.032] [http://hdl.handle.net/10807/70698]
The analgesic agent tapentadol inhibits calcitonin gene-related peptide release from isolated rat brainstem via a serotonergic mechanism
Greco, Maria Cristina;Navarra, Pierluigi;Tringali, Giuseppe
2015
Abstract
In this study we tested the hypothesis that tapentadol inhibits GGRP release from the rat brainstem through a mechanism mediated by the inhibition of NA reuptake; as a second alternative hypothesis, we investigated whether tapentadol inhibits GGRP release via the inhibition of 5-HT reuptake.
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