A description is given of the clinical, neuropsychological, and neuroimaging evolution of a 12-year-old boy (CG) who presented with bilateral thalamic astrocytoma (World Health Organization Grade 2). CG underwent an extensive neuropsychological assessment immediately after biopsy prior to any medical therapies and was followed up for 3 years until death. Neuropsychological functioning was thoroughly investigated by means of a detailed battery that included intelligence and cognitive functions. Evolution was characterized by cognitive deterioration that preceded neuroimaging signs of tumor progression. Starting from normal cognitive organization, the child exhibited visuospatial memory deficits and, afterward, diffuse cognitive impairment. The role of neuropsychological assessment in detecting early disease progression is discussed, mainly for rare pathologies whose evolution may be extremely variable.

Peruzzi, L., Iuvone, L., Ruggiero, A., Colosimo, C., Stefanini, M. C., Riccardi, R., Neuropsychological Deterioration Predicts Tumor Progression in a Young Boy With Bithalamic Glioma, <<APPLIED NEUROPSYCHOLOGY. CHILD>>, 2015; (N/A): 1-6. [doi:10.1080/21622965.2014.960566] [http://hdl.handle.net/10807/70059]

Neuropsychological Deterioration Predicts Tumor Progression in a Young Boy With Bithalamic Glioma

Peruzzi, Laura;Iuvone, Laura;Ruggiero, Antonio;Colosimo, Cesare;Stefanini, Maria Chiara;Riccardi, Riccardo
2015

Abstract

A description is given of the clinical, neuropsychological, and neuroimaging evolution of a 12-year-old boy (CG) who presented with bilateral thalamic astrocytoma (World Health Organization Grade 2). CG underwent an extensive neuropsychological assessment immediately after biopsy prior to any medical therapies and was followed up for 3 years until death. Neuropsychological functioning was thoroughly investigated by means of a detailed battery that included intelligence and cognitive functions. Evolution was characterized by cognitive deterioration that preceded neuroimaging signs of tumor progression. Starting from normal cognitive organization, the child exhibited visuospatial memory deficits and, afterward, diffuse cognitive impairment. The role of neuropsychological assessment in detecting early disease progression is discussed, mainly for rare pathologies whose evolution may be extremely variable.
Inglese
Peruzzi, L., Iuvone, L., Ruggiero, A., Colosimo, C., Stefanini, M. C., Riccardi, R., Neuropsychological Deterioration Predicts Tumor Progression in a Young Boy With Bithalamic Glioma, <<APPLIED NEUROPSYCHOLOGY. CHILD>>, 2015; (N/A): 1-6. [doi:10.1080/21622965.2014.960566] [http://hdl.handle.net/10807/70059]
File in questo prodotto:
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/10807/70059
Citazioni
  • ???jsp.display-item.citation.pmc??? 1
  • Scopus 2
  • ???jsp.display-item.citation.isi??? 2
social impact