The detection of antibodies binding neural antigens in patients with epilepsy has led to the definition of 'autoimmune epilepsy'. Patients with neural antibodies not responding to antiepileptic drugs (AEDs) may benefit from immunotherapy. Aim of this study was to evaluate the frequency of autoantibodies specific to neural antigens in patients with epilepsy and their response to immunotherapy.
Iorio, R., Assenza, G., Tombini, M., Colicchio, G., Della Marca, G., Benvenga, A., Damato, V., Rossini, P. M., Vollono, C., Plantone, D., Marti, A., Batocchi, A., Evoli, A., The detection of neural autoantibodies in patients with antiepileptic-drug-resistant epilepsy predicts response to immunotherapy, <<EUROPEAN JOURNAL OF NEUROLOGY>>, 2015; 22 (1): 70-78. [doi:10.1111/ene.12529] [http://hdl.handle.net/10807/69804]
The detection of neural autoantibodies in patients with antiepileptic-drug-resistant epilepsy predicts response to immunotherapy
Iorio, Raffaele;Colicchio, Gabriella;Della Marca, Giacomo;Rossini, Paolo Maria;Vollono, Catello;Evoli, Amelia
2015
Abstract
The detection of antibodies binding neural antigens in patients with epilepsy has led to the definition of 'autoimmune epilepsy'. Patients with neural antibodies not responding to antiepileptic drugs (AEDs) may benefit from immunotherapy. Aim of this study was to evaluate the frequency of autoantibodies specific to neural antigens in patients with epilepsy and their response to immunotherapy.
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