In recent years, Botulinum Toxin has been shown to be efficacious and safe in the treatment of sialorrhea, but scanty data are available on its long term use. The aim of this study was to investigate adverse events, discriminate differences in safety, and evaluate the efficacy of long-term use of both abobotulinumtoxinA and rimabotulinumtoxinB ultrasound-guided injections for sialorrhea in a retrospective trial. Moreover we review the literature on this topic.
Petracca, M., Guidubaldi, A., Ricciardi, L., Ialongo, T., Del Grande, A., Mulas, D., Di Stasio, E., Bentivoglio, A. R., Botulinum Toxin A and B in sialorrhea: Long-term data and literature overview, <<TOXICON>>, 2015; 107 (Pt A): 129-140. [doi:10.1016/j.toxicon.2015.08.014] [http://hdl.handle.net/10807/69796]
Botulinum Toxin A and B in sialorrhea: Long-term data and literature overview
Petracca, Martina;Guidubaldi, Arianna;Ialongo, Tamara;Del Grande, Alessandra;Mulas, Delia;Di Stasio, Enrico;Bentivoglio, Anna Rita
2015
Abstract
In recent years, Botulinum Toxin has been shown to be efficacious and safe in the treatment of sialorrhea, but scanty data are available on its long term use. The aim of this study was to investigate adverse events, discriminate differences in safety, and evaluate the efficacy of long-term use of both abobotulinumtoxinA and rimabotulinumtoxinB ultrasound-guided injections for sialorrhea in a retrospective trial. Moreover we review the literature on this topic.
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