No information is currently available regarding pancreatic cancer (PC) pattern of care in Italy. In the present study, a nationwide survey using a questionnaire was performed to enquire the local standards for PC diagnosis and radiotherapy treatment. Fifty-seven percent of 140 Italian centres completed questionnaire. The main causes of no radiotherapy indication were poor general condition (45%) and lack of guidelines (25%). Physicians (38%) employed neoadjuvant therapy in locally advanced PC patients, while in other centres (62%) adjuvant chemoradiation was administered. Adjuvant gemcitabine-based chemotherapy was selected as the treatment of choice by 59% of centres. Patients were treated mostly with doses of 50-54.9 Gy on the tumour (or bed) plus lymph nodes. A 3D-CRT technique was used in 81.2% of centres, while IMRT and IGRT were available in 61.2 and 48.7% of cases, respectively. Extensive variation exists with regard to patterns of care for PC in Italy. Nevertheless, cooperative studies emerging from this survey appeared beneficial.

Macchia, G., Sainato, A., Talamini, R., Boz, G., Bacigalupo, A., Caravatta, L., Fiore, M., Friso, M., Fusco, V., Lupattelli, M., Mantello, G., Mattiucci, G. C., Slim, N., Sciacero, P., Turri, L., Valentini, V., Morganti, A. G., Genovesi, D., Patterns of radiotherapy practice for pancreatic cancer: Results of the Gastrointestinal Radiation Oncology Study Group multi-institutional survey, <<ONCOLOGY REPORTS>>, 2015; 34 (1): 382-390. [doi:10.3892/or.2015.3955] [http://hdl.handle.net/10807/68250]

Patterns of radiotherapy practice for pancreatic cancer: Results of the Gastrointestinal Radiation Oncology Study Group multi-institutional survey

Macchia, Gabriella;Caravatta, Luciana;Fusco, Vincenzo;Mattiucci, Gian Carlo;Valentini, Vincenzo;Morganti, Alessio Giuseppe;
2015

Abstract

No information is currently available regarding pancreatic cancer (PC) pattern of care in Italy. In the present study, a nationwide survey using a questionnaire was performed to enquire the local standards for PC diagnosis and radiotherapy treatment. Fifty-seven percent of 140 Italian centres completed questionnaire. The main causes of no radiotherapy indication were poor general condition (45%) and lack of guidelines (25%). Physicians (38%) employed neoadjuvant therapy in locally advanced PC patients, while in other centres (62%) adjuvant chemoradiation was administered. Adjuvant gemcitabine-based chemotherapy was selected as the treatment of choice by 59% of centres. Patients were treated mostly with doses of 50-54.9 Gy on the tumour (or bed) plus lymph nodes. A 3D-CRT technique was used in 81.2% of centres, while IMRT and IGRT were available in 61.2 and 48.7% of cases, respectively. Extensive variation exists with regard to patterns of care for PC in Italy. Nevertheless, cooperative studies emerging from this survey appeared beneficial.
Inglese
Macchia, G., Sainato, A., Talamini, R., Boz, G., Bacigalupo, A., Caravatta, L., Fiore, M., Friso, M., Fusco, V., Lupattelli, M., Mantello, G., Mattiucci, G. C., Slim, N., Sciacero, P., Turri, L., Valentini, V., Morganti, A. G., Genovesi, D., Patterns of radiotherapy practice for pancreatic cancer: Results of the Gastrointestinal Radiation Oncology Study Group multi-institutional survey, <>, 2015; 34 (1): 382-390. [doi:10.3892/or.2015.3955] [http://hdl.handle.net/10807/68250]
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/10807/68250
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