We report pertussis cases in 4 infants less than 6 months admitted with symptoms compatible with pertussis to the intensive care unit of the Università Cattolica del Sacro Cuore in Rome, April 2014. Realtime PCR confirmed pertussis diagnosis for the 4 infants, 2 of them were cousins, and for the household contacts of 1 of them. Analysis of pertussis toxin, its promoter and pertactin was also performed. First of all, this report emphasizes the need to investigate household contact of infants with pertussis; secondly, to evaluate the selective vaccination of household members of newborns as an effective programme to reduce pertussis in infants.
Sali, M., Buttinelli, G., Fazio, C., Vacca, P., La Sorda, M., Carannante, A., Spanu, T., Valentini, P., Stefanelli, P., Pertussis in infants less than 6 months of age and household contacts, Italy April 2014, <<HUMAN VACCINES & IMMUNOTHERAPEUTICS>>, 2015; (Aprile): 1173-1174. [doi:10.1080/21645515.2015.1019190] [http://hdl.handle.net/10807/66950]
Pertussis in infants less than 6 months of age and household contacts, Italy April 2014
Sali, Michela;La Sorda, Marilena;Spanu, Teresa;Valentini, Piero;
2015
Abstract
We report pertussis cases in 4 infants less than 6 months admitted with symptoms compatible with pertussis to the intensive care unit of the Università Cattolica del Sacro Cuore in Rome, April 2014. Realtime PCR confirmed pertussis diagnosis for the 4 infants, 2 of them were cousins, and for the household contacts of 1 of them. Analysis of pertussis toxin, its promoter and pertactin was also performed. First of all, this report emphasizes the need to investigate household contact of infants with pertussis; secondly, to evaluate the selective vaccination of household members of newborns as an effective programme to reduce pertussis in infants.
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
