Critical impairment of adaptive immune response has been observed in patients with acute coronary syndromes (ACS) with reduced expansion of regulatory T cells (Treg) and enhanced effector T-cell responsiveness, both associated with poorer outcomes.

Flego, D., Severino, A., Trotta, F., Privitero, M., Ucci, S., Zara, C., Massaro, G., Pedicino, D., Biasucci, L. M., Liuzzo, G., Crea, F., Increased PTPN22 Expression and Defective CREB Activation Impair Regulatory T-Cell Differentiation in Non-ST-Segment Elevation Acute Coronary Syndromes, <<JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY>>, 2015; 65 (12): 1175-1186. [doi:10.1016/j.jacc.2015.01.027] [http://hdl.handle.net/10807/66135]

Increased PTPN22 Expression and Defective CREB Activation Impair Regulatory T-Cell Differentiation in Non-ST-Segment Elevation Acute Coronary Syndromes

Flego, Davide;Severino, Anna;Trotta, Francesco;Ucci, Sarassunta;Zara, Chiara;Pedicino, Daniela;Biasucci, Luigi Marzio;Liuzzo, Giovanna;Crea, Filippo
2015

Abstract

Critical impairment of adaptive immune response has been observed in patients with acute coronary syndromes (ACS) with reduced expansion of regulatory T cells (Treg) and enhanced effector T-cell responsiveness, both associated with poorer outcomes.
Inglese
Flego, D., Severino, A., Trotta, F., Privitero, M., Ucci, S., Zara, C., Massaro, G., Pedicino, D., Biasucci, L. M., Liuzzo, G., Crea, F., Increased PTPN22 Expression and Defective CREB Activation Impair Regulatory T-Cell Differentiation in Non-ST-Segment Elevation Acute Coronary Syndromes, <<JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY>>, 2015; 65 (12): 1175-1186. [doi:10.1016/j.jacc.2015.01.027] [http://hdl.handle.net/10807/66135]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10807/66135
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