Evidence favours insulin resistance and compensatory hyperinsulinemia as the predominant, perhaps primary, defects in polycystic ovary syndrome (PCOS). The aim of the present study was to evaluate insulin metabolism in young women with PCOS but normal glucose tolerance as compared with age, body mass index and insulin resistance-matched controls to answer the question whether women with PCOS hypersecrete insulin in comparison to appropriately insulin resistance-matched controls.
Manco, M., Castagneto Gissey, L., Arrighi, E., Carnicelli, A., Brufani, C., Luciano, R., Mingrone, G., Insulin dynamics in young women with polycystic ovary syndrome and normal glucose tolerance across categories of body mass index, <<PLOS ONE>>, 2014; 9 (4): e92995-e92995. [doi:10.1371/journal.pone.0092995] [http://hdl.handle.net/10807/64618]
Insulin dynamics in young women with polycystic ovary syndrome and normal glucose tolerance across categories of body mass index
Mingrone, Geltrude
2014
Abstract
Evidence favours insulin resistance and compensatory hyperinsulinemia as the predominant, perhaps primary, defects in polycystic ovary syndrome (PCOS). The aim of the present study was to evaluate insulin metabolism in young women with PCOS but normal glucose tolerance as compared with age, body mass index and insulin resistance-matched controls to answer the question whether women with PCOS hypersecrete insulin in comparison to appropriately insulin resistance-matched controls.
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