Several studies in the lamb model have shown that hyperinflation of the lungs early in life may cause a blunted response to surfactant with signs of lung injury and any attempt to recruit lung volume in the surfactant deficient preterm infant by large lung inflations at birth should be potentially dangerous. As regards the situation when surfactant is given later, as rescue treatment for established RDS, the evidence for a clinically beneficial effect of a recruitment maneuver is yet insufficient and, hopefully, future studies will gather more data on this aspect.

Vento, G., Tana, M., Tirone, C., Aurilia, C., Lio, A., Ricci, C., Gambacorta, M. A., Romagnoli, C., Lung recruitment strategies and surfactant in neonatal intensive care unit, <<ACTA BIO-MEDICA DE L'ATENEO PARMENSE>>, 2014; 85 (1): 11-14 [http://hdl.handle.net/10807/64587]

Lung recruitment strategies and surfactant in neonatal intensive care unit

Vento, Giovanni;Tana, Milena;Tirone, Chiara;Aurilia, Claudia;Lio, Alessandra;Ricci, Cinzia;Gambacorta, Maria Antonietta;Romagnoli, Costantino
2014

Abstract

Several studies in the lamb model have shown that hyperinflation of the lungs early in life may cause a blunted response to surfactant with signs of lung injury and any attempt to recruit lung volume in the surfactant deficient preterm infant by large lung inflations at birth should be potentially dangerous. As regards the situation when surfactant is given later, as rescue treatment for established RDS, the evidence for a clinically beneficial effect of a recruitment maneuver is yet insufficient and, hopefully, future studies will gather more data on this aspect.
Inglese
Vento, G., Tana, M., Tirone, C., Aurilia, C., Lio, A., Ricci, C., Gambacorta, M. A., Romagnoli, C., Lung recruitment strategies and surfactant in neonatal intensive care unit, <<ACTA BIO-MEDICA DE L'ATENEO PARMENSE>>, 2014; 85 (1): 11-14 [http://hdl.handle.net/10807/64587]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10807/64587
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