Gadobutrol (Gadavist) and gadoteridol (ProHance) have similar macrocyclic molecular structures, but gadobutrol is formulated at a 2-fold higher (1 mol/L versus 0.5 mol/L) concentration. We sought to determine whether this difference impacts morphologic contrast-enhanced MR imaging.
Maravilla, K., Smith, M., Vymazal, J., Goyal, M., Herman, M., Baima, J., Babbel, R., Vaneckova, M., Žižka, J., Colosimo, C., Urbańczyk Zawadzka, M., Mechl, M., Bag, A., Bastianello, S., Bueltmann, E., Hirai, T., Frattini, T., Kirchin, M., Pirovano, G., Are There Differences between Macrocyclic Gadolinium Contrast Agents for Brain Tumor Imaging? Results of a Multicenter Intraindividual Crossover Comparison of Gadobutrol with Gadoteridol (the TRUTH Study), <<AJNR, AMERICAN JOURNAL OF NEURORADIOLOGY>>, 2014; 36 (1): 14-23. [doi:10.3174/ajnr.A4154] [http://hdl.handle.net/10807/63729]
Are There Differences between Macrocyclic Gadolinium Contrast Agents for Brain Tumor Imaging? Results of a Multicenter Intraindividual Crossover Comparison of Gadobutrol with Gadoteridol (the TRUTH Study)
Colosimo, Cesare;
2014
Abstract
Gadobutrol (Gadavist) and gadoteridol (ProHance) have similar macrocyclic molecular structures, but gadobutrol is formulated at a 2-fold higher (1 mol/L versus 0.5 mol/L) concentration. We sought to determine whether this difference impacts morphologic contrast-enhanced MR imaging.
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