The fabrication of bioactive scaffolds able to mimic the in vivo cellular microenvironment represents a challenge for tissue engineering (TE). In the present work, we propose the combination of electrospinning (ESP) and soft-molecular imprinting (soft-MI) [1] to create a soft-molecular imprinted fibrous scaffold for TE applications. By combining these techniques, we fabricated poly-L-lactide acid (PLLA), PolyActive (PA) and poly lactic-co-glycolic acid (PLGA) based scaffolds functionalized using different protein arranged onto the surface.
Criscenti, G., Cerulli, G. G., Saris, D., Van Blitterswijk, C., Vozzi, G., Fernandes, H., Moroni, L., Realization of a soft-MI electrospun scaffold fortissue engineering applications, Abstract de <<Tissue Engineering & Regenerative Medicine International Society, European Chapter Meeting>>, (Genova, 10-13 June 2014 ), <<JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE>>, 2014; 2014 (8): 255-256. 10.1002/term.1932 [http://hdl.handle.net/10807/63100]
Realization of a soft-MI electrospun scaffold for tissue engineering applications
Cerulli, Giuliano Giorgio;
2014
Abstract
The fabrication of bioactive scaffolds able to mimic the in vivo cellular microenvironment represents a challenge for tissue engineering (TE). In the present work, we propose the combination of electrospinning (ESP) and soft-molecular imprinting (soft-MI) [1] to create a soft-molecular imprinted fibrous scaffold for TE applications. By combining these techniques, we fabricated poly-L-lactide acid (PLLA), PolyActive (PA) and poly lactic-co-glycolic acid (PLGA) based scaffolds functionalized using different protein arranged onto the surface.
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