The lithogenic character of human gallbladder bile was investigated by a mathematical model on the basis of a clinical data set. Each bile was described by means of the quaternary system bile salts--phospholipids--free fatty acids--cholesterol. Reporting a set of bile samples on the tetrahedron of concentrations, a clear separation emerged between the control bile, the bile from patients with gallstones, and the bile of subjects with gallbladder dyskinesia. This group was characterized by a largely increased content of free fatty acids.
Mingrone, G., Greco, A., Bertuzzi, A., Prediction of lithogenic character of human bile by a quaternary system, <<COMPUTERS AND BIOMEDICAL RESEARCH>>, 1986; 19 (4): 311-318 [http://hdl.handle.net/10807/6250]
Prediction of lithogenic character of human bile by a quaternary system
Mingrone, Geltrude;
1986
Abstract
The lithogenic character of human gallbladder bile was investigated by a mathematical model on the basis of a clinical data set. Each bile was described by means of the quaternary system bile salts--phospholipids--free fatty acids--cholesterol. Reporting a set of bile samples on the tetrahedron of concentrations, a clear separation emerged between the control bile, the bile from patients with gallstones, and the bile of subjects with gallbladder dyskinesia. This group was characterized by a largely increased content of free fatty acids.
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