PURPOSE: In oxygen-enhanced magnetic resonance imaging of the lung (O2-MRI), motion artifacts related to breathing hamper the quality of the parametric O2-maps. In this study, fully automatic non-rigid image registration was assessed as a post-processing method to improve the quality of O2-MRI. MATERIALS AND METHODS: Twenty healthy volunteers were investigated on a 1.5T MR system. O2-MRI was obtained in four coronal sections using an IR-HASTE sequence with TE/TI of 12/1200ms. Each section was repeatedly imaged during oxygen and room-air ventilation. Spatial differences among the images were corrected by fully automatic non-rigid registration. Signal variability, relative enhancement ratio between oxygen and room air images, and spatial heterogeneity of lung enhancement were assessed before and after image registration. RESULTS: Motion artifacts were corrected in 5-10s. Non-rigid registration reduced signal variability of the source images and heterogeneity of the O2-maps by 1.1±0.2% and 11.2±2.9%, respectively (p<0.0001). Registration did not influence O2 relative enhancement ratio (p=0.06). CONCLUSION: Fully automatic non-rigid image registration improves the quality of multislice oxygen-enhanced MRI of the lung.

Molinari, F., Bauman, G., Paolantonio, G., Geisler, T., Geiger, B., Bonomo, L., Kauczor, H., Puderbach, M., Improvement of multislice oxygen-enhanced MRI of the lung by fully automatic non-rigid image registration, <<EUROPEAN JOURNAL OF RADIOLOGY>>, 2011; (Novembre): N/A-N/A. [doi:10.1016/j.ejrad.2011.11.002] [http://hdl.handle.net/10807/6204]

Improvement of multislice oxygen-enhanced MRI of the lung by fully automatic non-rigid image registration

Molinari, Francesco;Paolantonio, Guglielmo;Bonomo, Lorenzo;
2011

Abstract

PURPOSE: In oxygen-enhanced magnetic resonance imaging of the lung (O2-MRI), motion artifacts related to breathing hamper the quality of the parametric O2-maps. In this study, fully automatic non-rigid image registration was assessed as a post-processing method to improve the quality of O2-MRI. MATERIALS AND METHODS: Twenty healthy volunteers were investigated on a 1.5T MR system. O2-MRI was obtained in four coronal sections using an IR-HASTE sequence with TE/TI of 12/1200ms. Each section was repeatedly imaged during oxygen and room-air ventilation. Spatial differences among the images were corrected by fully automatic non-rigid registration. Signal variability, relative enhancement ratio between oxygen and room air images, and spatial heterogeneity of lung enhancement were assessed before and after image registration. RESULTS: Motion artifacts were corrected in 5-10s. Non-rigid registration reduced signal variability of the source images and heterogeneity of the O2-maps by 1.1±0.2% and 11.2±2.9%, respectively (p<0.0001). Registration did not influence O2 relative enhancement ratio (p=0.06). CONCLUSION: Fully automatic non-rigid image registration improves the quality of multislice oxygen-enhanced MRI of the lung.
2011
Inglese
Molinari, F., Bauman, G., Paolantonio, G., Geisler, T., Geiger, B., Bonomo, L., Kauczor, H., Puderbach, M., Improvement of multislice oxygen-enhanced MRI of the lung by fully automatic non-rigid image registration, <<EUROPEAN JOURNAL OF RADIOLOGY>>, 2011; (Novembre): N/A-N/A. [doi:10.1016/j.ejrad.2011.11.002] [http://hdl.handle.net/10807/6204]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10807/6204
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