We sequenced the genomes of a ∼7,000-year-old farmer from Germany and eight ∼8,000-year-old hunter-gatherers from Luxembourg and Sweden. We analysed these and other ancient genomes with 2,345 contemporary humans to show that most present-day Europeans derive from at least three highly differentiated populations: west European hunter-gatherers, who contributed ancestry to all Europeans but not to Near Easterners; ancient north Eurasians related to Upper Palaeolithic Siberians, who contributed to both Europeans and Near Easterners; and early European farmers, who were mainly of Near Eastern origin but also harboured west European hunter-gatherer related ancestry. We model these populations' deep relationships and show that early European farmers had ∼44% ancestry from a 'basal Eurasian' population that split before the diversification of other non-African lineages.

Lazaridis, I., Patterson, N., Mittnik, A., Renaud, G., Mallick, S., Kirsanow, K., Sudmant, P., Schraiber, J., Castellano, S., Lipson, M., Berger, B., Economou, C., Bollongino, R., Fu, Q., Bos, K., Nordenfelt, S., Li, H., De Filippo, C., Prüfer, K., Sawyer, S., Posth, C., Haak, W., Hallgren, F., Fornander, E., Rohland, N., Delsate, D., Francken, M., Guinet, J., Wahl, J., Ayodo, G., Babiker, H., Bailliet, G., Balanovska, E., Balanovsky, O., Bedoya, G., Ben Ami, H., Bene, J., Berrada, F., Bravi, C., Brisighelli, F., Busby, G., Cali, F., Churnosov, M., Cole, D., Corach, D., Damba, L., Van Driem, G., Dryomov, S., Fedorova, S., Gallego Romero, I., Gubina, M., Hammer, M., Henn, B., Hervig, T., Hodoglugil, U., Jha, A., Karachanak Yankova, S., Khusainova, R., Khusnutdinova, E., Kittles, R., Kivisild, T., Kučinskas, V., Kushniarevich, A., Laredj, L., Litvinov, S., Loukidis, T., Mahley, R., Melegh, B., Metspalu, E., Molina, J., Mountain, J., Näkkäläjärvi, K., Nesheva, D., Nyambo, T., Osipova, L., Platonov, F., Posukh, O., Romano, V., Rothhammer, F., Rudan, I., Ruizbakiev, R., Sahakyan, H., Sajantila, A., Salas, A., Starikovskaya, E., Tarekegn, A., Toncheva, D., Turdikulova, S., Utevska, O., Vasquez, R., Villena, M., Voevoda, M., Winkler, C., Yepiskoposyan, L., Zalloua, P., Zemunik, T., Cooper, A., Capelli, C., Ruiz Linares, A., Tishkoff, S. E. A., Ancient human genomes suggest three ancestral populations for present-day Europeans, <<NATURE>>, 2014; 513 (7518): 409-413. [doi:10.1038/nature13673] [http://hdl.handle.net/10807/61469]

Ancient human genomes suggest three ancestral populations for present-day Europeans

Brisighelli, Francesca;
2014

Abstract

We sequenced the genomes of a ∼7,000-year-old farmer from Germany and eight ∼8,000-year-old hunter-gatherers from Luxembourg and Sweden. We analysed these and other ancient genomes with 2,345 contemporary humans to show that most present-day Europeans derive from at least three highly differentiated populations: west European hunter-gatherers, who contributed ancestry to all Europeans but not to Near Easterners; ancient north Eurasians related to Upper Palaeolithic Siberians, who contributed to both Europeans and Near Easterners; and early European farmers, who were mainly of Near Eastern origin but also harboured west European hunter-gatherer related ancestry. We model these populations' deep relationships and show that early European farmers had ∼44% ancestry from a 'basal Eurasian' population that split before the diversification of other non-African lineages.
2014
AREA05 - SCIENZE BIOLOGICHE
Pubblicazione su rivista con Impact Factor
Inglese
Articolo in rivista
Inglese
Agriculture
Asia
Europe
European Continental Ancestry Group
Genome, Human
History, Ancient
Humans
Population Dynamics
Principal Component Analysis
Settore BIO/08 - ANTROPOLOGIA
513
7518
2014
409
413
5
info:eu-repo/semantics/article
Lazaridis, I., Patterson, N., Mittnik, A., Renaud, G., Mallick, S., Kirsanow, K., Sudmant, P., Schraiber, J., Castellano, S., Lipson, M., Berger, B., Economou, C., Bollongino, R., Fu, Q., Bos, K., Nordenfelt, S., Li, H., De Filippo, C., Prüfer, K., Sawyer, S., Posth, C., Haak, W., Hallgren, F., Fornander, E., Rohland, N., Delsate, D., Francken, M., Guinet, J., Wahl, J., Ayodo, G., Babiker, H., Bailliet, G., Balanovska, E., Balanovsky, O., Bedoya, G., Ben Ami, H., Bene, J., Berrada, F., Bravi, C., Brisighelli, F., Busby, G., Cali, F., Churnosov, M., Cole, D., Corach, D., Damba, L., Van Driem, G., Dryomov, S., Fedorova, S., Gallego Romero, I., Gubina, M., Hammer, M., Henn, B., Hervig, T., Hodoglugil, U., Jha, A., Karachanak Yankova, S., Khusainova, R., Khusnutdinova, E., Kittles, R., Kivisild, T., Kučinskas, V., Kushniarevich, A., Laredj, L., Litvinov, S., Loukidis, T., Mahley, R., Melegh, B., Metspalu, E., Molina, J., Mountain, J., Näkkäläjärvi, K., Nesheva, D., Nyambo, T., Osipova, L., Platonov, F., Posukh, O., Romano, V., Rothhammer, F., Rudan, I., Ruizbakiev, R., Sahakyan, H., Sajantila, A., Salas, A., Starikovskaya, E., Tarekegn, A., Toncheva, D., Turdikulova, S., Utevska, O., Vasquez, R., Villena, M., Voevoda, M., Winkler, C., Yepiskoposyan, L., Zalloua, P., Zemunik, T., Cooper, A., Capelli, C., Ruiz Linares, A., Tishkoff, S. E. A., Ancient human genomes suggest three ancestral populations for present-day Europeans, <<NATURE>>, 2014; 513 (7518): 409-413. [doi:10.1038/nature13673] [http://hdl.handle.net/10807/61469]
none
262
Lazaridis, I; Patterson, N; Mittnik, A; Renaud, G; Mallick, S; Kirsanow, K; Sudmant, Ph; Schraiber, Jg; Castellano, S; Lipson, M; Berger, B; Economou,...espandi
100
art_per_29
03. Contributo in rivista::Articolo in rivista, Nota a sentenza
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10807/61469
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