The aim of the study was to evaluate expression of CD10 in a series of gastrointestinal tumors (GIST) and to find its relationship with prognosis, biological and clinical behavior. GISTs represent the most frequent gastrointestinal (GI) mesenchymal tumors. Biological behavior of GIST cannot be easily predicted; for this reason many biomolecular factors are being investigated to predict prognosis. Recently the role of the CD10 as prognostic predictor in the carcinogenesis of the gastrointestinal carcinomas has been accurately studied. To our knowledge, no data regarding the role of CD10 in GISTs have been published to date.
Caprino, P., Pericoli Ridolfini, M., Sofo, L., Carbone, A., Ricci, R., Rosa, F., Meloscia, A., Doglietto, G., Does CD10 expression individuate a GIST subgroup of patients?, <<MINERVA CHIRURGICA>>, 2014; 69 (5): 271-276 [http://hdl.handle.net/10807/61068]
Does CD10 expression individuate a GIST subgroup of patients?
Caprino, Paola;Pericoli Ridolfini, Marco;Sofo, Luigi;Carbone, Arnaldo;Ricci, Riccardo;Rosa, Fausto;Meloscia, Antonia;Doglietto, Giovanni
2014
Abstract
The aim of the study was to evaluate expression of CD10 in a series of gastrointestinal tumors (GIST) and to find its relationship with prognosis, biological and clinical behavior. GISTs represent the most frequent gastrointestinal (GI) mesenchymal tumors. Biological behavior of GIST cannot be easily predicted; for this reason many biomolecular factors are being investigated to predict prognosis. Recently the role of the CD10 as prognostic predictor in the carcinogenesis of the gastrointestinal carcinomas has been accurately studied. To our knowledge, no data regarding the role of CD10 in GISTs have been published to date.
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