The authors studied the binding of steroids with Blastokinin (BKN). They confirm that progesterone is the steroid that has a greater affinity for BKN than estradiol or testosterone; the latter is hardly bound to the protein at all. They also show that the presence of estradiol interferes with the formation phase of the BKN-progesterone complex, while testosterone does not. When the BKN-progesterone complex is already formed, a release of the progesterone occurs only when there is a double concentration of estradiol. The biological importance of this phenomenon is briefly discussed.

Garcea, N., Campo, S., Caruso, A., Milano, L., Bompiani, A., Binding of steroids to blastokinin, <<INTERNATIONAL JOURNAL OF FERTILITY>>, 1974; 19 (4): 197-201 [http://hdl.handle.net/10807/60983]

Binding of steroids to blastokinin

Garcea, Nicola;Campo, Sebastiano;Caruso, Alessandro;Bompiani, Adriano
1974

Abstract

The authors studied the binding of steroids with Blastokinin (BKN). They confirm that progesterone is the steroid that has a greater affinity for BKN than estradiol or testosterone; the latter is hardly bound to the protein at all. They also show that the presence of estradiol interferes with the formation phase of the BKN-progesterone complex, while testosterone does not. When the BKN-progesterone complex is already formed, a release of the progesterone occurs only when there is a double concentration of estradiol. The biological importance of this phenomenon is briefly discussed.
Inglese
Garcea, N., Campo, S., Caruso, A., Milano, L., Bompiani, A., Binding of steroids to blastokinin, <>, 1974; 19 (4): 197-201 [http://hdl.handle.net/10807/60983]
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/10807/60983
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