We evaluated the reliability of the Bruker Daltonik's MALDI Biotyper system in species-level identification of yeasts directly from blood culture bottles. Identification results were concordant with those of the conventional culture-based method for 95.9% of Candida albicans (187/195) and 86.5% of non-albicans Candida species (128/148). Results were available in 30 min (median), suggesting that this approach is a reliable, time-saving tool for routine identification of Candida species causing bloodstream infection.
Spanu, T., Posteraro, B., Fiori, B., D'Inzeo, T., Campoli, S., Ruggeri, A., Tumbarello, M., Canu, G., Trecarichi, E., Parisi, G., Tronci, M., Sanguinetti, M., Fadda, G., Directmaldi-tof mass spectrometry assay of blood culture broths for rapididentification of Candida species causing bloodstream infections: anobservational study in two large microbiology laboratories, <<JOURNAL OF CLINICAL MICROBIOLOGY>>, 2012; 50 (1): 176-179. [doi:10.1128/JCM.05742-11] [http://hdl.handle.net/10807/5779]
Direct maldi-tof mass spectrometry assay of blood culture broths for rapid identification of Candida species causing bloodstream infections: an observational study in two large microbiology laboratories
Spanu, Teresa;Posteraro, Brunella;Fiori, B;D'Inzeo, Tiziana;Tumbarello, Mario;Sanguinetti, Maurizio;Fadda, Giovanni
2012
Abstract
We evaluated the reliability of the Bruker Daltonik's MALDI Biotyper system in species-level identification of yeasts directly from blood culture bottles. Identification results were concordant with those of the conventional culture-based method for 95.9% of Candida albicans (187/195) and 86.5% of non-albicans Candida species (128/148). Results were available in 30 min (median), suggesting that this approach is a reliable, time-saving tool for routine identification of Candida species causing bloodstream infection.
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