Bone marrow- and adipose tissue-derived mesenchymal stromal cells (MSC) represent promising sources for regenerative medicine. However, the precise molecular mechanisms underlying MSC stemness maintenance versus differentiation are not fully understood. The aim of this study was to compare the genome-wide expression profiles of bone marrow-and adipose tissue-derived MSC, in order to identify a common molecular stemness core.
Saulnier, N., Puglisi, M. A., Lattanzi, W., Castellini, L., Pani, G., Leone, G., Alfieri, S., Michetti, F., Piscaglia, A., Gasbarrini, A., Gene profiling of bone marrow- and adipose tissue-derived stromal cells: a key role of Kruppel-like factor 4 in cell fate regulation, <<CYTOTHERAPY>>, 2011; 13 (3): 329-340. [doi:10.3109/14653249.2010.515576] [http://hdl.handle.net/10807/5750]
Gene profiling of bone marrow- and adipose tissue-derived stromal cells: a key role of Kruppel-like factor 4 in cell fate regulation
Saulnier, Nathalie;Puglisi, Maria Ausiliatrice;Lattanzi, Wanda;Pani, Giovambattista;Leone, Giuseppe;Alfieri, Sergio;Michetti, Fabrizio;Gasbarrini, Antonio
2011
Abstract
Bone marrow- and adipose tissue-derived mesenchymal stromal cells (MSC) represent promising sources for regenerative medicine. However, the precise molecular mechanisms underlying MSC stemness maintenance versus differentiation are not fully understood. The aim of this study was to compare the genome-wide expression profiles of bone marrow-and adipose tissue-derived MSC, in order to identify a common molecular stemness core.
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