It is generally assumed that visual cortical cells homogeneously shift their ocular dominance (OD) in response to monocular deprivation (MD), however little experimental evidence directly supports this notion. By using immunohistochemistry for the activity-dependent markers c-Fos and Arc, coupled with staining for markers of inhibitory cortical sub-populations, we studied whether long-term MD initiated at P21 differentially affects visual response of inhibitory neurons in rat binocular primary visual cortex.

Mainardi, M., Landi, S., Berardi, N., Maffei, L., Pizzorusso, T., Reduced responsiveness to long-term monocular deprivation of parvalbumin neurons assessed by c-Fos staining in rat visual cortex, <<PLOS ONE>>, 2009; 4 (2): e4342-e4342. [doi:10.1371/journal.pone.0004342] [http://hdl.handle.net/10807/57477]

Reduced responsiveness to long-term monocular deprivation of parvalbumin neurons assessed by c-Fos staining in rat visual cortex

Mainardi, Marco;
2009

Abstract

It is generally assumed that visual cortical cells homogeneously shift their ocular dominance (OD) in response to monocular deprivation (MD), however little experimental evidence directly supports this notion. By using immunohistochemistry for the activity-dependent markers c-Fos and Arc, coupled with staining for markers of inhibitory cortical sub-populations, we studied whether long-term MD initiated at P21 differentially affects visual response of inhibitory neurons in rat binocular primary visual cortex.
eng
Mainardi, M., Landi, S., Berardi, N., Maffei, L., Pizzorusso, T., Reduced responsiveness to long-term monocular deprivation of parvalbumin neurons assessed by c-Fos staining in rat visual cortex, <>, 2009; 4 (2): e4342-e4342. [doi:10.1371/journal.pone.0004342] [http://hdl.handle.net/10807/57477]
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/10807/57477
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