Brain-derived neurotrophic factor (BDNF) gene variants may potentially influence behaviour. In order to test this hypothesis, we investigated the relationship between BDNF Val66Met polymorphism and aggressive behaviour in a population of schizophrenic patients. Our results showed that increased number of BDNF Met alleles was associated with increased aggressive behaviour.
Spalletta, G., Morris, D., Angelucci, F., Rubino, I., Spoletini, I., Bria, P., Martinotti, G., Siracusano, A., Bonaviri, G., Bernardini, S., Caltagirone, C., Bossù, P., Donohoe, G., Gill, M., Corvin, A., BDNF Val66Met polymorphism is associated with aggressive behavior in schizophrenia, <<European psychiatry : the journal of the Association of European Psychiatrists>>, N/A; 25 (6): 311-313. [doi:10.1016/j.eurpsy.2009.10.008] [http://hdl.handle.net/10807/56956]
BDNF Val66Met polymorphism is associated with aggressive behavior in schizophrenia
Spalletta, Gianfranco;Spoletini, Ilaria;Bria, Pietro;Martinotti, Giovanni;
2010
Abstract
Brain-derived neurotrophic factor (BDNF) gene variants may potentially influence behaviour. In order to test this hypothesis, we investigated the relationship between BDNF Val66Met polymorphism and aggressive behaviour in a population of schizophrenic patients. Our results showed that increased number of BDNF Met alleles was associated with increased aggressive behaviour.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.