Concomitant primary cutaneous melanoma in monozygotic twins has been reported in only two pairs but in neither of them genetic analysis was performed. Two high-penetrance susceptibility genes, CDKN2A and CDK4 and one low-penetrance gene, MC1R, are well-defined genetic risk factors for melanoma. MITF has been recently identified as a novel intermediate risk melanoma-predisposing gene.

Pellegrini, C., Fargnoli, M., Suppa, M., Peris, K., MC1R variants predisposing to concomitant primary cutaneous melanoma in a monozygotic twin pair, <<BMC MEDICAL GENETICS>>, 2012; 13 (Settembre): 81-81. [doi:10.1186/1471-2350-13-81] [http://hdl.handle.net/10807/56394]

MC1R variants predisposing to concomitant primary cutaneous melanoma in a monozygotic twin pair

Peris, Ketty
2012

Abstract

Concomitant primary cutaneous melanoma in monozygotic twins has been reported in only two pairs but in neither of them genetic analysis was performed. Two high-penetrance susceptibility genes, CDKN2A and CDK4 and one low-penetrance gene, MC1R, are well-defined genetic risk factors for melanoma. MITF has been recently identified as a novel intermediate risk melanoma-predisposing gene.
Inglese
Pellegrini, C., Fargnoli, M., Suppa, M., Peris, K., MC1R variants predisposing to concomitant primary cutaneous melanoma in a monozygotic twin pair, <>, 2012; 13 (Settembre): 81-81. [doi:10.1186/1471-2350-13-81] [http://hdl.handle.net/10807/56394]
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/10807/56394
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