Ependymoma management remains challenging because of the inherent chemoresistance of this tumor. To determine whether ependymoma stem cells (SCs) might contribute to therapy resistance, we investigated the sensitivity of ependymoma SCs to temozolomide and etoposide.
Meco, D., Servidei, T., Lamorte, G., Binda, E., Arena, V., Riccardi, R., Ependymoma stem cells are highly sensitive to temozolomide in vitro and in orthotopic models, <<NEURO-ONCOLOGY>>, N/A; (N/A): N/A-N/A. [doi:10.1093/neuonc/nou008] [http://hdl.handle.net/10807/55973]
Ependymoma stem cells are highly sensitive to temozolomide in vitro and in orthotopic models
Meco, Daniela;Servidei, Tiziana;Arena, Vincenzo;Riccardi, Riccardo
2014
Abstract
Ependymoma management remains challenging because of the inherent chemoresistance of this tumor. To determine whether ependymoma stem cells (SCs) might contribute to therapy resistance, we investigated the sensitivity of ependymoma SCs to temozolomide and etoposide.
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