PURPOSE:To investigate the effects of sub-Tenon's capsule ropivacaine injection on pupillary diameter in strabismus surgery. METHODS: A total of 16 patients were randomly assigned to 2 groups. The ropivacaine group (R) received sub-Tenon's ropivacaine 1% (2.5-3 mL) injections. In the control group (C), general anesthesia was induced and a saline solution (2.5-3 mL) was injected in the sub-Tenon's capsule. Pupillary diameter was measured at baseline and 2 and 5 minutes from the injections. The effects of the injections were expressed as a ratio of final (5 minutes) versus basal diameter. RESULTS: A significant mydriasis occurred in the ropivacaine group when compared with the control group (Group R vs Group C ratio = 2.32, p < 0.0001) or with unoperated fellow eye (R vs unoperated eye ratio = 2.29, p < 0.0001). CONCLUSIONS: Ropivacaine in the sub-Tenon's capsule induces a mydriasis probably related to a pharmacological ciliary ganglion block. Copyright 2010 American Association for Pediatric Ophthalmology and Strabismus. Published by Mosby, Inc. All rights reserved.
Savino, G., Perrotta, V., Colucci, D., Balia, L., Garra, R., Petroni, S., Balestrazzi, E., Sammartino Sinicalco, M., Mydriasis induced by sub-Tenon's ropivacaine: injection in patients undergoing strabismus surgery, <<JOURNAL OF AAPOS>>, 2010; (Febbraio): 124-126. [doi:10.1016/j.jaapos.2009.11.022] [http://hdl.handle.net/10807/55759]
Mydriasis induced by sub-Tenon's ropivacaine: injection in patients undergoing strabismus surgery
Savino, Gustavo;Perrotta, Vittoria;Colucci, Daniela;Balia, Laura;Garra, Rossella;Petroni, Sergio;Balestrazzi, Emilio;Sammartino Sinicalco, Maria
2010
Abstract
PURPOSE:To investigate the effects of sub-Tenon's capsule ropivacaine injection on pupillary diameter in strabismus surgery. METHODS: A total of 16 patients were randomly assigned to 2 groups. The ropivacaine group (R) received sub-Tenon's ropivacaine 1% (2.5-3 mL) injections. In the control group (C), general anesthesia was induced and a saline solution (2.5-3 mL) was injected in the sub-Tenon's capsule. Pupillary diameter was measured at baseline and 2 and 5 minutes from the injections. The effects of the injections were expressed as a ratio of final (5 minutes) versus basal diameter. RESULTS: A significant mydriasis occurred in the ropivacaine group when compared with the control group (Group R vs Group C ratio = 2.32, p < 0.0001) or with unoperated fellow eye (R vs unoperated eye ratio = 2.29, p < 0.0001). CONCLUSIONS: Ropivacaine in the sub-Tenon's capsule induces a mydriasis probably related to a pharmacological ciliary ganglion block. Copyright 2010 American Association for Pediatric Ophthalmology and Strabismus. Published by Mosby, Inc. All rights reserved.
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