Growing evidence is now available on the use of S100B protein as a valuable marker of brain damage and its role as a neurotrophic factor. Bearing in mind, among different S100B protein properties that are still being investigated, the possibility of measuring this protein in different biological fluids renders it suitable for use in several disciplines. This is the case with perinatal medicine where even more noninvasive techniques are particularly desirable in order to ensure the minimal handling diagnostic and therapeutic strategies. In this setting, the present minireview reports data on the presence and the usefulness of S100B protein as brain damage marker and as a neurotrophic factor in the so-called unconventional biological fluids such as saliva and human milk, respectively. Results offer new possibilities for the use of S100B in perinatal medicine as a key-protein for the investigations focusing on central nervous system development and damage.

Gazzolo, D., Michetti, F., Perinatal S100B Protein Assessment in Human Unconventional Biological Fluids: a Minireview and New Perspectives, <<CARDIOVASCULAR PSYCHIATRY AND NEUROLOGY>>, 2010; (June 16): N/A-N/A. [doi:2010:703563] [http://hdl.handle.net/10807/5417]

Perinatal S100B Protein Assessment in Human Unconventional Biological Fluids: a Minireview and New Perspectives

Michetti, Fabrizio
2010

Abstract

Growing evidence is now available on the use of S100B protein as a valuable marker of brain damage and its role as a neurotrophic factor. Bearing in mind, among different S100B protein properties that are still being investigated, the possibility of measuring this protein in different biological fluids renders it suitable for use in several disciplines. This is the case with perinatal medicine where even more noninvasive techniques are particularly desirable in order to ensure the minimal handling diagnostic and therapeutic strategies. In this setting, the present minireview reports data on the presence and the usefulness of S100B protein as brain damage marker and as a neurotrophic factor in the so-called unconventional biological fluids such as saliva and human milk, respectively. Results offer new possibilities for the use of S100B in perinatal medicine as a key-protein for the investigations focusing on central nervous system development and damage.
Inglese
Gazzolo, D., Michetti, F., Perinatal S100B Protein Assessment in Human Unconventional Biological Fluids: a Minireview and New Perspectives, <<CARDIOVASCULAR PSYCHIATRY AND NEUROLOGY>>, 2010; (June 16): N/A-N/A. [doi:2010:703563] [http://hdl.handle.net/10807/5417]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10807/5417
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