Pulmonary embolism can be a catastrophic event that can result in early death or serious hemodynamic dysfunction. The dehydration, immobility, and infections occurring in acute stroke patients puts these patients at risk of developing deep vein thrombosis and pulmonary embolism. Recombinant tissue-type plasminogen activator (rt-PA) is the established therapy for acute ischemic stroke, and its prompt administration results in a better outcome in stroke patients. We describe a 73-year-old man who arrived at the emergency room within 2 hours of acute onset of left hemiparesis who was treated with rt-PA and suffered a pulmonary embolism 3 days after acute stroke therapy. rt-PA is also a current therapy for pulmonary embolism, but an ischemic stroke in the previous 3 months is an absolute contraindication to thrombolysis because of the high risk of intracranial hemorrhage. We discuss clinical and therapeutic decisions and review the current literature.

Pilato, F., Calandrelli, R., Profice, P., Della Marca, G., Broccolini, A., Bello, G., Bocci, M. G., Distefano, M., Colosimo, C., Rossini, P. M., Pulmonary embolism in a stroke patient after systemic thrombolysis: clinical decisions and literature review, <<JOURNAL OF STROKE AND CEREBROVASCULAR DISEASES>>, 2013; 22 (8): e667-e667-70. [doi:10.1016/j.jstrokecerebrovasdis.2013.06.016] [http://hdl.handle.net/10807/54072]

Pulmonary embolism in a stroke patient after systemic thrombolysis: clinical decisions and literature review

Pilato, Fabio;Calandrelli, Rosalinda;Profice, Paolo;Della Marca, Giacomo;Broccolini, Aldobrando;Bello, Giuseppe;Bocci, Maria Grazia;Distefano, Marisa;Colosimo, Cesare;Rossini, Paolo Maria
2013

Abstract

Pulmonary embolism can be a catastrophic event that can result in early death or serious hemodynamic dysfunction. The dehydration, immobility, and infections occurring in acute stroke patients puts these patients at risk of developing deep vein thrombosis and pulmonary embolism. Recombinant tissue-type plasminogen activator (rt-PA) is the established therapy for acute ischemic stroke, and its prompt administration results in a better outcome in stroke patients. We describe a 73-year-old man who arrived at the emergency room within 2 hours of acute onset of left hemiparesis who was treated with rt-PA and suffered a pulmonary embolism 3 days after acute stroke therapy. rt-PA is also a current therapy for pulmonary embolism, but an ischemic stroke in the previous 3 months is an absolute contraindication to thrombolysis because of the high risk of intracranial hemorrhage. We discuss clinical and therapeutic decisions and review the current literature.
Inglese
Pilato, F., Calandrelli, R., Profice, P., Della Marca, G., Broccolini, A., Bello, G., Bocci, M. G., Distefano, M., Colosimo, C., Rossini, P. M., Pulmonary embolism in a stroke patient after systemic thrombolysis: clinical decisions and literature review, <<JOURNAL OF STROKE AND CEREBROVASCULAR DISEASES>>, 2013; 22 (8): e667-e667-70. [doi:10.1016/j.jstrokecerebrovasdis.2013.06.016] [http://hdl.handle.net/10807/54072]
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/10807/54072
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