Several morphological and functional imaging techniques are usually used to detect residual/recurrent medullary thyroid carcinoma (MTC) with variable results; currently, there is growing interest in positron emission tomography (PET) methodology. Herein, we report our experience of and a literature review about the comparison of different positron emission tomography (PET) tracers in patients with residual/recurrent MTC. (18)F-DOPA PET/CT seems to be the most useful imaging method to detect recurrent MTC lesions, performing better than (18)F-FDG and (68)Ga-somatostatin analogs PET/CT. (18)F-FDG may complement (18)F-DOPA in patients with aggressive tumors. (68)Ga-somatostatin analogs PET/CT may be useful to select patients who could benefit from radioreceptor therapy. The information provided by the various PET tracers reflects different metabolic pathways, and may help to select the most appropriate treatment

Treglia, G., Castaldi, P., Villani, M. F., Perotti, G., Filice, A., Ambrosini, V., Cremonini, N., Versari, A., Fanti, S., Giordano, A., Rufini, V., Comparison of different positron emission tomography tracers in patients withrecurrent medullary thyroid carcinoma: our experience and a review of theliterature, <<RECENT RESULTS IN CANCER RESEARCH>>, 2013; 194 (N/A): 385-393 [http://hdl.handle.net/10807/53903]

Comparison of different positron emission tomography tracers in patients with recurrent medullary thyroid carcinoma: our experience and a review of the literature

Treglia, Giorgio;Castaldi, Paola;Villani, Maria Felicia;Perotti, Germano;Giordano, Alessandro;Rufini, Vittoria
2013

Abstract

Several morphological and functional imaging techniques are usually used to detect residual/recurrent medullary thyroid carcinoma (MTC) with variable results; currently, there is growing interest in positron emission tomography (PET) methodology. Herein, we report our experience of and a literature review about the comparison of different positron emission tomography (PET) tracers in patients with residual/recurrent MTC. (18)F-DOPA PET/CT seems to be the most useful imaging method to detect recurrent MTC lesions, performing better than (18)F-FDG and (68)Ga-somatostatin analogs PET/CT. (18)F-FDG may complement (18)F-DOPA in patients with aggressive tumors. (68)Ga-somatostatin analogs PET/CT may be useful to select patients who could benefit from radioreceptor therapy. The information provided by the various PET tracers reflects different metabolic pathways, and may help to select the most appropriate treatment
Inglese
Treglia, G., Castaldi, P., Villani, M. F., Perotti, G., Filice, A., Ambrosini, V., Cremonini, N., Versari, A., Fanti, S., Giordano, A., Rufini, V., Comparison of different positron emission tomography tracers in patients withrecurrent medullary thyroid carcinoma: our experience and a review of theliterature, <<RECENT RESULTS IN CANCER RESEARCH>>, 2013; 194 (N/A): 385-393 [http://hdl.handle.net/10807/53903]
File in questo prodotto:
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/10807/53903
Citazioni
  • ???jsp.display-item.citation.pmc??? 4
  • Scopus 16
  • ???jsp.display-item.citation.isi??? ND
social impact