Pancreaticoduodenectomy is the standard care for invasive ampullary adenocarcinomas. However, endoscopic snare papillectomy (ESP) might play a curative role in very selected patients. We studied a series of 15 patients with T1 ampullary adenocarcinoma who were treated by ESP alone and followed up for a mean of 29.6 ± 21.9 months (range 8 - 81 months). ESP was curative for eight patients (57.1 %). No tumor-related death was observed in patients with a cancer infiltration depth of ≤ 4 mm. According to this preliminary experience, we suggest that this measurable variable threshold should be considered as a possible basis for future large-scale studies.
Petrone, G., Ricci, R., Familiari, P., Inzani, F., Matsuoka, M., Mutignani, M., Delle Fave, G., Costamagna, G., Rindi, G., Endoscopic snare papillectomy: a possible radical treatment for a subgroup of T1 ampullary adenocarcinomas, <<ENDOSCOPY>>, 2013; 45 (5): 401-404. [doi:10.1055/s-0032-1326213] [http://hdl.handle.net/10807/53794]
Endoscopic snare papillectomy: a possible radical treatment for a subgroup of T1 ampullary adenocarcinomas
Familiari, Pietro;Mutignani, Massimiliano;Costamagna, Guido;
2013
Abstract
Pancreaticoduodenectomy is the standard care for invasive ampullary adenocarcinomas. However, endoscopic snare papillectomy (ESP) might play a curative role in very selected patients. We studied a series of 15 patients with T1 ampullary adenocarcinoma who were treated by ESP alone and followed up for a mean of 29.6 ± 21.9 months (range 8 - 81 months). ESP was curative for eight patients (57.1 %). No tumor-related death was observed in patients with a cancer infiltration depth of ≤ 4 mm. According to this preliminary experience, we suggest that this measurable variable threshold should be considered as a possible basis for future large-scale studies.
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