Metformin has been reported to reduce the risk of gestational diabetes (GD) in women with polycystic ovarian syndrome (PCOS). However, little is known about the mechanisms of action of this drug during pregnancy. In the attempt to fill this gap, we performed a prospective longitudinal study providing a detailed examination of glucose and insulin metabolism in pregnant women with PCOS undergoing metformin therapy.

Romualdi, D., De Cicco, S., Gagliano, D., Busacca, M., Campagna, G., Lanzone, A., Guido, M., How metformin acts in PCOS pregnant women: insights into insulin secretion and peripheral action at each trimester of gestation, <<DIABETES CARE>>, 2013; 36 (6): 1477-1482. [doi:10.2337/dc12-2071] [http://hdl.handle.net/10807/53318]

How metformin acts in PCOS pregnant women: insights into insulin secretion and peripheral action at each trimester of gestation

Romualdi, Daniela;De Cicco, Simona;Lanzone, Antonio;Guido, Maurizio
2013

Abstract

Metformin has been reported to reduce the risk of gestational diabetes (GD) in women with polycystic ovarian syndrome (PCOS). However, little is known about the mechanisms of action of this drug during pregnancy. In the attempt to fill this gap, we performed a prospective longitudinal study providing a detailed examination of glucose and insulin metabolism in pregnant women with PCOS undergoing metformin therapy.
Inglese
Romualdi, D., De Cicco, S., Gagliano, D., Busacca, M., Campagna, G., Lanzone, A., Guido, M., How metformin acts in PCOS pregnant women: insights into insulin secretion and peripheral action at each trimester of gestation, <<DIABETES CARE>>, 2013; 36 (6): 1477-1482. [doi:10.2337/dc12-2071] [http://hdl.handle.net/10807/53318]
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/10807/53318
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