A 33-year old man underwent an F-FDG PET/CT searching for the cause of a fever of unknown origin. F-FDG PET/CT incidentally detected a focal area of markedly increased radiopharmaceutical uptake corresponding to a 2.5-cm nodule in the right adrenal gland. Laboratory data ruled out the presence of a functioning adrenal lesion. All these findings were suggestive of adrenal malignancy. After right adrenalectomy, histology showed a benign solitary fibrous tumor of the adrenal gland. This case highlights that benign solitary fibrous tumor should be considered as possible false-positive F-FDG PET/CT finding for malignancy in evaluating adrenal incidentalomas.
Treglia, G., Oragano, L., Fadda, G., Raffaelli, M., Lombardi, C. P., Castaldi, P., Rufini, V., A Rare Case of Solitary Fibrous Tumor of the Adrenal Gland Detected by 18F-FDG PET/CT, <<CLINICAL NUCLEAR MEDICINE>>, 2014; 39 (5): 475-477. [doi:10.1097/RLU.0b013e31828e9752] [http://hdl.handle.net/10807/53160]
A Rare Case of Solitary Fibrous Tumor of the Adrenal Gland Detected by 18F-FDG PET/CT
Treglia, Giorgio;Oragano, Luigi;Fadda, Guido;Raffaelli, Marco;Lombardi, Celestino Pio;Castaldi, Paola;Rufini, Vittoria
2013
Abstract
A 33-year old man underwent an F-FDG PET/CT searching for the cause of a fever of unknown origin. F-FDG PET/CT incidentally detected a focal area of markedly increased radiopharmaceutical uptake corresponding to a 2.5-cm nodule in the right adrenal gland. Laboratory data ruled out the presence of a functioning adrenal lesion. All these findings were suggestive of adrenal malignancy. After right adrenalectomy, histology showed a benign solitary fibrous tumor of the adrenal gland. This case highlights that benign solitary fibrous tumor should be considered as possible false-positive F-FDG PET/CT finding for malignancy in evaluating adrenal incidentalomas.
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