Nutrient availability and nutrient-dependent biochemical signals represent major determinants of cellular senescence and organismal aging. The present chapter describes simple procedures to reliably evaluate the response of cultured cell to nutrients through the longevity protein p66(SHC1) and the mTOR/S6K cascade, which might be used to study cellular senescence and its chemical modulation by pharmaceutical agents in vitro.

Ranieri, S., Pani, G., Monitoring nutrient signaling through the longevity protein p66(SHC¹), <<METHODS IN MOLECULAR BIOLOGY>>, 2013; 965 (N/A): 341-353. [doi:10.1007/978-1-62703-239-1_23] [http://hdl.handle.net/10807/52408]

Monitoring nutrient signaling through the longevity protein p66(SHC¹)

Pani, Giovambattista
2013

Abstract

Nutrient availability and nutrient-dependent biochemical signals represent major determinants of cellular senescence and organismal aging. The present chapter describes simple procedures to reliably evaluate the response of cultured cell to nutrients through the longevity protein p66(SHC1) and the mTOR/S6K cascade, which might be used to study cellular senescence and its chemical modulation by pharmaceutical agents in vitro.
Inglese
Ranieri, S., Pani, G., Monitoring nutrient signaling through the longevity protein p66(SHC¹), <<METHODS IN MOLECULAR BIOLOGY>>, 2013; 965 (N/A): 341-353. [doi:10.1007/978-1-62703-239-1_23] [http://hdl.handle.net/10807/52408]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10807/52408
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