Among somatic stem cells, those residing in the intestine represent a fascinating and poorly explored research field. Particularly, somatic stem cells reside in the small intestine at the level of the crypt base, in a constant balance between self-renewal and differentiation. Aim of the present review is to delve into the mechanisms that regulate the delicate equilibrium through which intestinal stem cells orchestrate intestinal architecture. To this aim, special focus will be addressed to identify the integrating signals from the surrounding niche, supporting a model whereby distinct cell populations facilitate homeostatic vs injury-induced regeneration.

Tesori, V., Puglisi, M. A., Lattanzi, W., Gasbarrini, G., Gasbarrini, A., Update on small intestinal stem cells, <<WORLD JOURNAL OF GASTROENTEROLOGY>>, 2013; 19 (29): 4671-4678. [doi:10.3748/wjg.v19.i29.4671] [http://hdl.handle.net/10807/52156]

Update on small intestinal stem cells

Tesori, Valentina;Puglisi, Maria Ausiliatrice;Gasbarrini, Antonio
2013

Abstract

Among somatic stem cells, those residing in the intestine represent a fascinating and poorly explored research field. Particularly, somatic stem cells reside in the small intestine at the level of the crypt base, in a constant balance between self-renewal and differentiation. Aim of the present review is to delve into the mechanisms that regulate the delicate equilibrium through which intestinal stem cells orchestrate intestinal architecture. To this aim, special focus will be addressed to identify the integrating signals from the surrounding niche, supporting a model whereby distinct cell populations facilitate homeostatic vs injury-induced regeneration.
2013
Inglese
Tesori, V., Puglisi, M. A., Lattanzi, W., Gasbarrini, G., Gasbarrini, A., Update on small intestinal stem cells, <<WORLD JOURNAL OF GASTROENTEROLOGY>>, 2013; 19 (29): 4671-4678. [doi:10.3748/wjg.v19.i29.4671] [http://hdl.handle.net/10807/52156]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10807/52156
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